Unplanned hospitalizations in patients with locoregionally advanced head and neck cancer treated with (chemo)radiotherapy with and without prophylactic percutaneous endoscopic gastrostomy.

Bojaxhiu, Beat; Shrestha, Binaya Kumar; Luterbacher, Pascal; Eliçin, Olgun; Shelan, Mohamed; Macpherson, Andrew J. S.; Heimgartner, Benjamin; Giger, Roland; Aebersold, Daniel; Zaugg, Kathrin (2020). Unplanned hospitalizations in patients with locoregionally advanced head and neck cancer treated with (chemo)radiotherapy with and without prophylactic percutaneous endoscopic gastrostomy. Radiation oncology, 15(1), p. 281. BioMed Central 10.1186/s13014-020-01727-9

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BACKGROUND

Current studies about percutaneous endoscopic gastrostomy (PEG) tube placement report equivalent patient outcomes with prophylactic PEG tubes (pPEGs) versus common nutritional support. Unreported was if omitting a pPEG is associated with an increased risk of complications leading to a treatment-related unplanned hospitalization (TRUH).

METHODS

TRUHs were retrospectively analyzed in patients with advanced head and neck squamous cell carcinoma (n = 310) undergoing (chemo)radiotherapy with (pPEG) or without PEG (nPEG).

RESULTS

In 88 patients (28%), TRUH was reported. One of the leading causes of TRUH in nPEG patients was inadequate oral intake (n = 16, 13%), and in pPEG patients, complications after PEG tube insertion (n = 12, 10%). Risk factors for TRUH were poor performance status, tobacco use, and surgical procedures.

CONCLUSIONS

Omitting pPEG tube placement without increasing the risk of an unplanned hospitalization due to dysphagia, dehydration or malnutrition, is an option in patients being carefully monitored. Patients aged > 60 years with hypopharyngeal carcinoma, tobacco consumption, and poor performance status appear at risk of PEG tube-related complications leading to an unplanned hospitalization.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Radiation Oncology
04 Faculty of Medicine > Faculty Institutions > Teaching Staff, Faculty of Medicine
04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Clinic of Nuclear Medicine
04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Ear, Nose and Throat Disorders (ENT)
04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine
04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine > Gastroenterology

UniBE Contributor:

Bojaxhiu, Beat; Shrestha, Binaya Kumar; Eliçin, Olgun; Shelan, Mohamed; Macpherson, Andrew; Heimgartner, Benjamin Thomas; Giger, Roland; Aebersold, Daniel and Zaugg, Kathrin

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1748-717X

Publisher:

BioMed Central

Language:

English

Submitter:

Sabine Lanz

Date Deposited:

06 Jan 2021 10:51

Last Modified:

17 Mar 2021 04:46

Publisher DOI:

10.1186/s13014-020-01727-9

PubMed ID:

33317602

Uncontrolled Keywords:

Head and neck cancer Morbidity PEG Percutaneous endoscopic gastrostomy Radiotherapy

BORIS DOI:

10.48350/150166

URI:

https://boris.unibe.ch/id/eprint/150166

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