The right anterior temporal lobe critically contributes to magnitude knowledge

Pflugshaupt, Tobias; Bauer, Daniel; Frey, Julia; Vanbellingen, Tim; Kaufmann, Brigitte C.; Bohlhalter, Stephan; Nyffeler, Thomas (2020). The right anterior temporal lobe critically contributes to magnitude knowledge. Brain Communications, 2(2), fcaa157. Oxford University Press 10.1093/braincomms/fcaa157

[img]
Preview
Text
fcaa157.pdf - Published Version
Available under License Creative Commons: Attribution-Noncommercial (CC-BY-NC).

Download (594kB) | Preview

Cognitive estimation is a mental ability applied to solve numerical problems when precise facts are unknown, unavailable or impractical to calculate. It has been associated with several underlying cognitive components, most often with executive functions and semantic memory. Little is known about the neural correlates of cognitive estimation. To address this issue, the present cross-sectional study applied lesion-symptom mapping in a group of 55 patients with left hemineglect due to right-hemisphere stroke. Previous evidence suggests a high prevalence of cognitive estimation impairment in these patients, as they might show a general bias towards large magnitudes. Compared to 55 age- and gender-matched healthy controls, the patient group demonstrated impaired cognitive estimation. However, the expected large magnitude bias was not found. Lesion-symptom mapping related their general estimation impairment predominantly to brain damage in the right anterior temporal lobe. Also critically involved were the right uncinate fasciculus, the anterior commissure and the right inferior frontal gyrus. The main findings of this study emphasize the role of semantic memory in cognitive estimation, with reference to a growing body of neuroscientific literature postulating a transmodal hub for semantic cognition situated in the bilateral anterior temporal lobe. That such semantic hub function may also apply to numerical knowledge is not undisputed. We here propose a critical contribution of the right anterior temporal lobe to at least one aspect of number processing, i.e. the knowledge about real-world numerical magnitudes.

Item Type:

Journal Article (Original Article)

Division/Institute:

10 Strategic Research Centers > ARTORG Center for Biomedical Engineering Research > ARTORG Center - Gerontechnology and Rehabilitation

UniBE Contributor:

Vanbellingen, Tim; Kaufmann, Brigitte; Bohlhalter, Stephan and Nyffeler, Thomas

Subjects:

600 Technology > 610 Medicine & health

ISSN:

2632-1297

Publisher:

Oxford University Press

Language:

English

Submitter:

Angela Amira Botros

Date Deposited:

13 Jan 2021 11:57

Last Modified:

17 Jan 2021 02:55

Publisher DOI:

10.1093/braincomms/fcaa157

PubMed ID:

33225278

BORIS DOI:

10.7892/boris.150587

URI:

https://boris.unibe.ch/id/eprint/150587

Actions (login required)

Edit item Edit item
Provide Feedback