Risk Factors for Postprocedural Arterial Ischemic Stroke in Children With Cardiac Disease.

Henzi, Bettina C.; Brotschi, Barbara; Balmer, Christian; Hennig, Bert; Rimensberger, Peter; Perez, Marie-Hélène; Pfammatter, Jean-Pierre; Beghetti, Maurice; Sekarski, Nicole; Datta, Alexandre N; Fluss, Joel; Faignart, Nicole; Hackenberg, Annette; Regényi, Mária; Steinlin, Maja; Hug, Maja I (2020). Risk Factors for Postprocedural Arterial Ischemic Stroke in Children With Cardiac Disease. Stroke, 51(9), e242-e245. Lippincott Williams & Wilkins 10.1161/STROKEAHA.120.029447

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BACKGROUND AND PURPOSE

Cardiac pathologies are the second most frequent risk factor (RF) in children with arterial ischemic stroke (AIS). This study aimed to analyze RFs for AIS in children with cardiac disease and cardiac intervention.

METHODS

Data were drawn from the Swiss Neuropediatric Stroke Registry. Patients with cardiac disease and postprocedural AIS registered from 2000 until 2015 were analyzed for the cause of cardiac disease and for potential RFs.

RESULTS

Forty-seven out of 78 children with cardiac disease had a cardiac intervention. Of these, 36 presented a postprocedural AIS. Median time from cardiac intervention to symptom onset was 4 days (interquartile range, 2-8.5); time to diagnosis of AIS was 2 days (interquartile range, 0-5.8). Main RFs for postprocedural AIS were hypotension, prosthetic cardiac material, right-to-left shunt, arrhythmias, low cardiac output, and infections.

CONCLUSIONS

In children with postprocedural AIS, time to diagnosis was delayed. Most patients presented multiple potentially modifiable RFs as hemodynamic alterations and infections.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Paediatric Medicine
04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiology
04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Paediatric Medicine > Neuropaediatrics

UniBE Contributor:

Henzi, Bettina Cornelia; Hennig, Bert; Pfammatter, Jean-Pierre; Regényi, Mária and Steinlin, Maja

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0039-2499

Publisher:

Lippincott Williams & Wilkins

Language:

English

Submitter:

Karen Lidzba

Date Deposited:

27 Jan 2021 11:15

Last Modified:

28 Jan 2021 10:44

Publisher DOI:

10.1161/STROKEAHA.120.029447

PubMed ID:

32811375

Uncontrolled Keywords:

hemodynamics hypotension incidence infections low cardiac output

BORIS DOI:

10.48350/150623

URI:

https://boris.unibe.ch/id/eprint/150623

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