Planar and single-photon emission computed tomography imaging in dogs with thyroid tumors: 68 cases.

van den Berg, Marit F; Daminet, Sylvie; Stock, Emmelie; Vandermeulen, Eva; Scheemaeker, Stephanie; Campos, Miguel; Kooistra, Hans S; Galac, Sara; Duchateau, Luc; Peremans, Kathelijne (2020). Planar and single-photon emission computed tomography imaging in dogs with thyroid tumors: 68 cases. Journal of veterinary internal medicine, 34(6), pp. 2651-2659. Wiley-Blackwell 10.1111/jvim.15908

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BACKGROUND

Information on scintigraphy findings in dogs with thyroid neoplasia is scarce. The use of single-photon emission computed tomography (SPECT) could improve detection of metastatic disease.

HYPOTHESIS/OBJECTIVES

To describe planar and SPECT imaging findings in dogs with thyroid tumors, and to compare SPECT and thoracic radiography for metastasis detection.

ANIMALS

Sixty-eight dogs with thyroid neoplasia.

METHODS

Retrospective study, search of medical records for dogs with thyroid neoplasia (2008-2018).

RESULTS

Thyroid scintigraphy was available from 68 dogs, of which 6 presented after surgical resection. Radionuclide uptake was increased in 56% of dogs, decreased in 24%, and comparable to that of the salivary glands in 13%. The remainder had multiple masses with variable uptake. A homogeneous uptake pattern was present in 16% and a heterogeneous uptake pattern in 73%. In 11% (all dogs with multiple masses), various uptake patterns were present. Thyroid tumors were well delineated in 55%. There was a significant association between hormone status and uptake pattern (P = .009), with a heterogeneous uptake pattern in the majority of euthyroid dogs, and hormone status and tumor circumscription (P = .003), with well-circumscribed margins in the majority of hypothyroid and hyperthyroid dogs. Thoracic SPECT imaging was available in 39 dogs and identified metastatic lesions in 15 dogs. Thoracic radiographs were performed in 14 of these dogs, and detected metastases in 3 dogs.

CONCLUSIONS AND CLINICAL IMPORTANCE

SPECT imaging is a viable imaging technique to screen for thoracic metastasis and wider use of SPECT imaging is recommended in dogs with thyroid neoplasia.

Item Type:

Journal Article (Original Article)

Division/Institute:

05 Veterinary Medicine > Department of Clinical Veterinary Medicine (DKV) > Small Animal Clinic > Small Animal Clinic, Internal Medicine
05 Veterinary Medicine > Department of Clinical Veterinary Medicine (DKV) > Small Animal Clinic

UniBE Contributor:

Campos, Miguel

Subjects:

500 Science > 570 Life sciences; biology
500 Science > 590 Animals (Zoology)
600 Technology > 630 Agriculture

ISSN:

0891-6640

Publisher:

Wiley-Blackwell

Language:

English

Submitter:

Miguel Fonseca e Campos

Date Deposited:

11 Jan 2021 10:31

Last Modified:

17 Mar 2021 04:57

Publisher DOI:

10.1111/jvim.15908

PubMed ID:

32978987

Uncontrolled Keywords:

canine metastasis scintigraphy thyroid neoplasia

BORIS DOI:

10.48350/150763

URI:

https://boris.unibe.ch/id/eprint/150763

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