Increased level of antibodies cross-reacting with Ves v 5 and CRISP-2 in MAR-positive patients

Brunner-Agten, Saskia; Pavlovic, Rodoljub; Müller, Lorenz; Horn, Michael Peter; Huber, Andreas R.; Stadler, Beda Martin; Vogel, Monique (2013). Increased level of antibodies cross-reacting with Ves v 5 and CRISP-2 in MAR-positive patients. International archives of allergy and immunology, 160(1), pp. 47-55. Basel: Karger 10.1159/000338946

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Anti-sperm antibodies (ASA) have been described to be involved in immunological infertility. A possible antigen for ASA is the human cysteine-rich secretory protein 2 (CRISP-2), a sperm surface protein important in sperm-oocyte interaction. Furthermore, anti-CRISP-2 antibodies were shown to decrease fertility rates in vitro. Recently, we have reported cross-reacting antibodies recognizing CRISP-2 and antigen 5 from yellow jacket venom (Ves v 5) in human serum.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Institute for Immunology (discontinued)

UniBE Contributor:

Pavlovic, Rodoljub; Müller, Lorenz; Horn, Michael Peter; Huber, Andreas R.; Stadler, Beda Martin and Vogel, Monique

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1018-2438

Publisher:

Karger

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:37

Last Modified:

11 Sep 2014 20:38

Publisher DOI:

10.1159/000338946

PubMed ID:

22948171

Web of Science ID:

000311487100007

URI:

https://boris.unibe.ch/id/eprint/15095 (FactScience: 222288)

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