Population-based design of mandibular fixation plates with bone quality and morphology considerations

Bousleiman, Habib; Iizuka, Tateyuki; Nolte, Lutz-Peter; Reyes, Mauricio (2013). Population-based design of mandibular fixation plates with bone quality and morphology considerations. Annals of biomedical engineering, 41(2), pp. 377-384. Cambridge: Springer US; http://www.springer-ny.com 10.1007/s10439-012-0671-8

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In this paper we present a new population-based implant design methodology, which advances the state-of-the-art approaches by combining shape and bone quality information into the design strategy. The method may enhance the mechanical stability of the fixation and reduces the intra-operative in-plane bending which might impede the functionality of the locking mechanism. The computational method is presented for the case of mandibular locking fixation plates, where the mandibular angle and the bone quality at screw locations are taken into account. The method automatically derives the mandibular angle and the bone thickness and intensity values at the path of every screw from a set of computed tomography images. An optimization strategy is then used to optimize the two parameters of plate angle and screw position. The method was applied to two populations of different genders. Results for the new design are presented along with a comparison with a commercially available mandibular locking fixation plate (MODUS(®) TriLock(®) 2.0/2.3/2.5, Medartis AG, Basel, Switzerland). The proposed designs resulted in a statistically significant improvement in the available bone thickness when compared to the standard plate. There is a higher probability that the proposed implants cover areas of thicker cortical bone without compromising the bone mineral density around the screws. The obtained results allowed us to conclude that an angle and screw separation of 129° and 9 mm for females and 121° and 10 mm for males are more suitable designs than the commercially available 120° and 9 mm.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Pre-clinic Human Medicine > Institute for Surgical Technology & Biomechanics ISTB
04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Craniomaxillofacial Surgery

UniBE Contributor:

Bou Sleiman, Habib; Iizuka, Tateyuki; Nolte, Lutz-Peter and Reyes, Mauricio

Subjects:

500 Science > 570 Life sciences; biology
600 Technology > 610 Medicine & health

ISSN:

0090-6964

Publisher:

Springer US; http://www.springer-ny.com

Language:

English

Submitter:

Mauricio Antonio Reyes Aguirre

Date Deposited:

04 Oct 2013 14:37

Last Modified:

23 Oct 2019 00:09

Publisher DOI:

10.1007/s10439-012-0671-8

PubMed ID:

23053302

Web of Science ID:

000313432200014

BORIS DOI:

10.7892/boris.15097

URI:

https://boris.unibe.ch/id/eprint/15097 (FactScience: 222298)

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