The indication for fertility preservation in women with Turner syndrome should not only be based on the ovarian reserve but also on the genotype and expected future health status.

Nawroth, Frank; Schüring, Andreas N; von Wolff, Michael (2020). The indication for fertility preservation in women with Turner syndrome should not only be based on the ovarian reserve but also on the genotype and expected future health status. Acta obstetricia et gynecologica Scandinavica, 99(12), pp. 1579-1583. Wiley-Blackwell 10.1111/aogs.13984

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Fertility preservation in women with Turner syndrome is highly controversial. Some strongly recommend freezing of ovarian tissue at a young age, others do not. The controversy is partly due to different perspectives and professions. Biologists prefer to freeze young ovaries with high follicle density, reproductive physicians want to avoid risky operations and iatrogenic infertility by removing one ovary, and cardiologists and obstetricians warn against the risks of later pregnancies. Accordingly, fertility preservation in young women with Turner syndrome is more than just the freezing of ovarian tissue or oocytes. Fertility preservation requires a balanced decision considering the conservation of fertility, the protection of reproductive health, and future health consequences. Therefore, fertility preservation strategies should be based not only on the individual ovarian reserve but also on the genotype and the expected cardiac health status to decide what is the best option: to freeze tissue or alternatively to wait and see.

Item Type:

Journal Article (Further Contribution)

Division/Institute:

04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Gynaecology

UniBE Contributor:

von Wolff, Michael

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0001-6349

Publisher:

Wiley-Blackwell

Language:

English

Submitter:

Monika Zehr

Date Deposited:

12 Jan 2021 16:40

Last Modified:

12 Jan 2021 16:40

Publisher DOI:

10.1111/aogs.13984

PubMed ID:

32860418

Uncontrolled Keywords:

Turner syndrome fertility preservation health oocyte cryopreservation ovarian cryopreservation ovarian stimulation pregnancy

BORIS DOI:

10.48350/150975

URI:

https://boris.unibe.ch/id/eprint/150975

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