Local Burden of Disease Vaccine Coverage, Collaborators (2021). Mapping routine measles vaccination in low- and middle-income countries. Nature, 589(7842), pp. 415-419. Springer Nature 10.1038/s41586-020-03043-4
|
Text
Mapping_routine.pdf - Published Version Available under License Creative Commons: Attribution (CC-BY). Download (59MB) | Preview |
The safe, highly effective measles vaccine has been recommended globally since 1974, yet in 2017 there were more than 17 million cases of measles and 83,400 deaths in children under 5 years old, and more than 99% of both occurred in low- and middle-income countries (LMICs)1-4. Globally comparable, annual, local estimates of routine first-dose measles-containing vaccine (MCV1) coverage are critical for understanding geographically precise immunity patterns, progress towards the targets of the Global Vaccine Action Plan (GVAP), and high-risk areas amid disruptions to vaccination programmes caused by coronavirus disease 2019 (COVID-19)5-8. Here we generated annual estimates of routine childhood MCV1 coverage at 5 × 5-km2 pixel and second administrative levels from 2000 to 2019 in 101 LMICs, quantified geographical inequality and assessed vaccination status by geographical remoteness. After widespread MCV1 gains from 2000 to 2010, coverage regressed in more than half of the districts between 2010 and 2019, leaving many LMICs far from the GVAP goal of 80% coverage in all districts by 2019. MCV1 coverage was lower in rural than in urban locations, although a larger proportion of unvaccinated children overall lived in urban locations; strategies to provide essential vaccination services should address both geographical contexts. These results provide a tool for decision-makers to strengthen routine MCV1 immunization programmes and provide equitable disease protection for all children.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiology |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1476-4687 |
Publisher: |
Springer Nature |
Language: |
English |
Submitter: |
Nadia Biscozzo |
Date Deposited: |
02 Feb 2021 15:13 |
Last Modified: |
13 Mar 2021 04:12 |
Publisher DOI: |
10.1038/s41586-020-03043-4 |
PubMed ID: |
33328634 |
Additional Information: |
Thomas Pilgrim is a member of the 'Local Burden of Disease Vaccine Coverage Collaborators'. |
BORIS DOI: |
10.48350/151131 |
URI: |
https://boris.unibe.ch/id/eprint/151131 |
Actions (login required)
 |
Edit item |