Feasibility of a Dielectric Elastomer Augmented Aorta

Almanza, Morgan; Clavica, Francesco; Chavanne, Jonathan; Moser, David; Obrist, Dominik; Carrel, Thierry; Civet, Yoan; Perriard, Yves (2021). Feasibility of a Dielectric Elastomer Augmented Aorta. Advanced science, 8(6), p. 2001974. Wiley 10.1002/advs.202001974

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Although heart transplantation is a gold standard for severe heart failure, there is a need for alternative effective therapies. A dielectric‐elastomer aorta is used to augment the physiological role of the aorta in the human circulatory system. To this end, the authors developed a tubular dielectric elastomer actuator (DEA) able to assist the heart by easing the deformation of the aorta in the systole and by increasing its recoil force in the diastole. In vitro experiments using a pulsatile flow‐loop, replicating human physiological flow and pressure conditions, show a reduction of 5.5% (47 mJ per cycle) of the heart energy with this device. Here, the controlled stiffness of the DEA graft, which is usually difficult to exploit for actuators, is perfectly matching the assistance principle. At the same time, the physiological aortic pressure is exploited to offer a prestretch to the DEA which otherwise would require an additional bulky pre‐stretching system to reach high performances.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiovascular Surgery
10 Strategic Research Centers > ARTORG Center for Biomedical Engineering Research > ARTORG Center - Cardiovascular Engineering (CVE)

UniBE Contributor:

Clavica, Francesco; Obrist, Dominik and Carrel, Thierry

Subjects:

600 Technology > 610 Medicine & health
600 Technology > 620 Engineering

ISSN:

2198-3844

Publisher:

Wiley

Language:

English

Submitter:

Francesco Clavica

Date Deposited:

15 Feb 2021 17:10

Last Modified:

21 Mar 2021 03:00

Publisher DOI:

10.1002/advs.202001974

BORIS DOI:

10.48350/151998

URI:

https://boris.unibe.ch/id/eprint/151998

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