Fabrication of Human Anatomy-Based Scala Tympani Models with a Hydrophilic Coating for Cochlear Implant Insertion Experiments

Aebischer, Philipp; Caversaccio, Marco; Wimmer, Wilhelm (2021). Fabrication of Human Anatomy-Based Scala Tympani Models with a Hydrophilic Coating for Cochlear Implant Insertion Experiments. Hearing research, 404, p. 108205. Elsevier 10.1016/j.heares.2021.108205

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Electrode array insertion into the inner ear is a critical step in cochlear implantation, and artificial scala tympani models can be a valuable tool for studying the dynamics of this process.

This technical note describes the fabrication of electrode array dummies and scala tympani models that address shortcomings of previously published cochlear models. In particular, we improve the reproduction of frictional properties with an easy-to-apply polymer brush coating that creates hydrophilic surfaces, and produce geometries with accurate macro-anatomy based on microtomographic scans. The presented methods rely only on commonly available materials and tools and are based on publicly available data.

Our validation shows very good agreement of insertion forces both in terms of linear insertion depth and insertion speed compared to previously published measurements of insertions in cadaveric temporal bones.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Ear, Nose and Throat Disorders (ENT)
10 Strategic Research Centers > ARTORG Center for Biomedical Engineering Research > ARTORG Center - Hearing Research Laboratory

Graduate School:

Graduate School for Cellular and Biomedical Sciences (GCB)

UniBE Contributor:

Aebischer, Philipp; Caversaccio, Marco and Wimmer, Wilhelm

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0378-5955

Publisher:

Elsevier

Language:

English

Submitter:

Wilhelm Wimmer

Date Deposited:

17 Feb 2021 11:32

Last Modified:

28 Feb 2021 02:57

Publisher DOI:

10.1016/j.heares.2021.108205

BORIS DOI:

10.48350/152366

URI:

https://boris.unibe.ch/id/eprint/152366

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