Communication and ethical considerations for fertility preservation for patients with childhood, adolescent, and young adult cancer: recommendations from the PanCareLIFE Consortium and the International Late Effects of Childhood Cancer Guideline Harmonization Group.

Mulder, Renée L; Font-Gonzalez, Anna; van Dulmen-den Broeder, Eline; Quinn, Gwendolyn P; Ginsberg, Jill P; Loeffen, Erik A H; Hudson, Melissa M; Burns, Karen C; van Santen, Hanneke M; Berger, Claire; Diesch, Tamara; Dirksen, Uta; Giwercman, Aleksander; Gracia, Clarisa; Hunter, Sarah E; Kelvin, Joanne F; Klosky, James L; Laven, Joop S E; Lockart, Barbara A; Neggers, Sebastian J C M M; ... (2021). Communication and ethical considerations for fertility preservation for patients with childhood, adolescent, and young adult cancer: recommendations from the PanCareLIFE Consortium and the International Late Effects of Childhood Cancer Guideline Harmonization Group. The lancet oncology, 22(2), e68-e80. Elsevier 10.1016/S1470-2045(20)30595-7

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Patients with childhood, adolescent, and young adult cancer who will be treated with gonadotoxic therapies are at increased risk for infertility. Many patients and their families desire biological children but effective communication about treatment-related infertility risk and procedures for fertility preservation does not always happen. The PanCareLIFE Consortium and the International Late Effects of Childhood Cancer Guideline Harmonization Group reviewed the literature and developed a clinical practice guideline that provides recommendations for ongoing communication methods for fertility preservation for patients who were diagnosed with childhood, adolescent, and young adult cancer at age 25 years or younger and their families. Moreover, the guideline panel formulated considerations of the ethical implications that are associated with these procedures. Grading of Recommendations Assessment, Development and Evaluation methodology was used to grade the evidence and recommendations. In this clinical practice guideline, existing evidence and international expertise are combined to develop transparent recommendations that are easy to use to facilitate ongoing communication between health-care providers and patients with childhood, adolescent, and young adult cancer who might be at high risk for fertility impairment and their families.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Paediatric Medicine
04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Paediatric Medicine > Paediatric Haematology/Oncology

UniBE Contributor:

Tinner Oehler, Eva Maria Eugenia

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1474-5488

Publisher:

Elsevier

Language:

English

Submitter:

Jacqueline Pillichody Ruch

Date Deposited:

17 Feb 2021 16:24

Last Modified:

18 Feb 2021 15:55

Publisher DOI:

10.1016/S1470-2045(20)30595-7

PubMed ID:

33539755

BORIS DOI:

10.48350/152410

URI:

https://boris.unibe.ch/id/eprint/152410

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