Elimination of local abnormal ventricular activities: a new end point for substrate modification in patients with scar-related ventricular tachycardia

Jaïs, Pierre; Maury, Philippe; Khairy, Paul; Sacher, Frédéric; Nault, Isabelle; Komatsu, Yuki; Hocini, Mélèze; Forclaz, Andrei; Jadidi, Amir S; Weerasooryia, Rukshen; Shah, Ashok; Derval, Nicolas; Cochet, Hubert; Knecht, Sebastien; Miyazaki, Shinsuke; Linton, Nick; Rivard, Lena; Wright, Matthew; Wilton, Stephen B; Scherr, Daniel; ... (2012). Elimination of local abnormal ventricular activities: a new end point for substrate modification in patients with scar-related ventricular tachycardia. Circulation, 125(18), pp. 2184-96. Baltimore, Md.: Lippincott Williams & Wilkins 10.1161/CIRCULATIONAHA.111.043216

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Catheter ablation of ventricular tachycardia (VT) is effective and particularly useful in patients with frequent defibrillator interventions. Various substrate modification techniques have been described for unmappable or hemodynamically intolerable VT. Noninducibility is the most frequently used end point but is associated with significant limitations, so the optimal end point remains unclear. We hypothesized that elimination of local abnormal ventricular activities (LAVAs) during sinus rhythm or ventricular pacing would be a useful and effective end point for substrate-based VT ablation. As an adjunct to this strategy, we used a new high-density mapping catheter and frequently used epicardial mapping.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiology

UniBE Contributor:

Roten, Laurent

ISSN:

0009-7322

Publisher:

Lippincott Williams & Wilkins

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:38

Last Modified:

17 Mar 2015 21:30

Publisher DOI:

10.1161/CIRCULATIONAHA.111.043216

PubMed ID:

22492578

Web of Science ID:

000306962600011

URI:

https://boris.unibe.ch/id/eprint/15291 (FactScience: 222600)

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