Ming, Xiu-Fen; Rajapakse, Angana G; Yepuri, Gautham; Xiong, Yuyan; Carvas, João M; Ruffieux, Jean; Scerri, Isabelle; Wu, Zongsong; Popp, Katja; Li, Jianhui; Sartori, Claudio; Scherrer, Urs; Kwak, Brenda R; Montani, Jean-Pierre; Yang, Zhihong (2012). Arginase II Promotes Macrophage Inflammatory Responses Through Mitochondrial Reactive Oxygen Species, Contributing to Insulin Resistance and Atherogenesis. Journal of the American Heart Association, 1(4), e000992. New York, N.Y.: American Heart Association
Full text not available from this repository. (Request a copy)Macrophage-mediated chronic inflammation is mechanistically linked to insulin resistance and atherosclerosis. Although arginase I is considered antiinflammatory, the role of arginase II (Arg-II) in macrophage function remains elusive. This study characterizes the role of Arg-II in macrophage inflammatory responses and its impact on obesity-linked type II diabetes mellitus and atherosclerosis.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiology |
UniBE Contributor: |
Scherrer, Urs |
ISSN: |
2047-9980 |
Publisher: |
American Heart Association |
Language: |
English |
Submitter: |
Factscience Import |
Date Deposited: |
04 Oct 2013 14:38 |
Last Modified: |
05 Dec 2022 14:11 |
PubMed ID: |
23130157 |
URI: |
https://boris.unibe.ch/id/eprint/15297 (FactScience: 222606) |
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