Breast Cancer

Sager, Patrizia; von Wolff, Michael; Fehm, Tanja (2020). Breast Cancer. In: von Wolff, Michael; Nawroth, Frank (eds.) Fertility Preservation in Oncological and Non-Oncological Diseases (pp. 33-42). Cham: Springer 10.1007/978-3-030-47568-0_6

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Breast cancer is the most common cancer in young women. Fortunately, the survival rates are very high, especially in the early stages. Chemotherapy can lead to amenorrhea and infertility, especially in women >30 years of age. The most common chemotherapies impose a significant risk of premature ovarian insufficiency, especially in women >30 years of age. In these women GnRH agonists, freezing of oocytes and freezing of ovarian tissue alone or in combination are options to preserve fertility. If ovarian stimulation is chosen, aromatase inhibitors should be added in estrogen-sensitive cancer to reduce estrogen blood concentrations.

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