Turner Syndrome

Schüring, Andreas; Nawroth, Frank; von Wolff, Michael (2020). Turner Syndrome. In: von Wolff, Michael; Nawroth, Frank (eds.) Fertility Preservation in Oncological and Non-Oncological Diseases (pp. 145-156). Cham: Springer 10.1007/978-3-030-47568-0_17

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Turner syndrome (TS) summarises a heterogeneous group of patients with different chromosomal pathologies, including 45,X0 monosomy, mosaicism and structural abnormalities of the X chromosome. Monosomies usually lead to very early premature ovarian insufficiency, whereas mosaicism and structural abnormalities may preserve fertility. The genotype should therefore be taken into account in the indication for and implementation of a fertility preservation measure. The increased pregnancy risks in Turner syndrome must also be considered. Fertility preservation measures include freezing of oocytes and possibly ovarian tissue.

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