Treatment of Uterine Bleeding During Chemotherapy

Sänger, Nicole; von Wolff, Michael; Nawroth, Frank (2020). Treatment of Uterine Bleeding During Chemotherapy. In: von Wolff, Michael; Nawroth, Frank (eds.) Fertility Preservation in Oncological and Non-Oncological Diseases (pp. 253-260). Cham: Springer 10.1007/978-3-030-47568-0_28

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The administration of gonadotoxic agents (e.g. during chemotherapy) in premenopausal women can lead to vaginal bleeding disorders and pose a difficult treatment situation for oncological specialists. This chapter describes practical treatment options for serious vaginal bleeding events by considering hormonal and non-hormonal drugs (such as e.g. oral contraceptives, GnRH agonists, tranexamic acid). A distinction is made between prevention of bleedings and treatment for acute bleeding, stating possible medications, medical combinations and dosages. Radiological or surgical interventional procedures are also discussed, although they are rarely used.

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