High NRBP1 expression in prostate cancer is linked with poor clinical outcomes and increased cancer cell growth

Ruiz, Christian; Oeggerli, Martin; Germann, Markus; Gluderer, Silvia; Stocker, Hugo; Andreozzi, Mariacarla; Thalmann, George N; Cecchini, Marco G; Zellweger, Tobias; Stürm, Susanna; Koivisto, Pasi A; Helin, Heikki J; Gelmann, Edward P; Glass, Andrew G; Gasser, Thomas C; Terracciano, Luigi M; Bachmann, Alexander; Wyler, Stephen; Bubendorf, Lukas and Rentsch, Cyrill A (2012). High NRBP1 expression in prostate cancer is linked with poor clinical outcomes and increased cancer cell growth. Prostate, 72(15), pp. 1678-87. Hoboken, N.J.: Wiley-Blackwell 10.1002/pros.22521

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We recently established the rationale that NRBP1 (nuclear receptor binding protein 1) has a potential growth-promoting role in cell biology. NRBP1 interacts directly with TSC-22, a potential tumor suppressor gene that is differently expressed in prostate cancer. Consequently, we analyzed the role of NRBP1 expression in prostate cancer cell lines and its expression on prostate cancer tissue microarrays (TMA).

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Urology

UniBE Contributor:

Thalmann, George

ISSN:

0270-4137

Publisher:

Wiley-Blackwell

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:38

Last Modified:

17 Mar 2015 21:31

Publisher DOI:

10.1002/pros.22521

PubMed ID:

22473923

Web of Science ID:

000309405800009

URI:

https://boris.unibe.ch/id/eprint/15432 (FactScience: 222777)

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