Clinical features and practical diagnosis of bullous pemphigoid

Schmidt, Enno; della Torre, Rocco; Borradori, Luca (2012). Clinical features and practical diagnosis of bullous pemphigoid. Immunology and allergy clinics of North America, 32(2), 217-32, v. Philadelphia, Pa.: Elsevier 10.1016/j.iac.2012.04.002

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Bullous pemphigoid (BP) represents the most common autoimmune subepidermal blistering disease. BP typically affects the elderly and is associated with significant morbidity. It has usually a chronic course with spontaneous exacerbations. The cutaneous manifestations of BP can be extremely protean. While diagnosis of BP in the bullous stage is straightforward, in the non-bullous stage or in atypical variants of BP signs and symptoms are frequently non-specific with eg, only itchy excoriated, eczematous, papular and/or urticarial lesions that may persist for several weeks or months. Diagnosis of BP critically relies on immunopathologic examinations including direct immunofluorescence microscopy and detection of serum autoantibodies by indirect immunofluorescence microscopy or BP180-ELISA.

Item Type:

Journal Article (Further Contribution)

Division/Institute:

04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Dermatology

UniBE Contributor:

Borradori, Luca

ISSN:

0889-8561

Publisher:

Elsevier

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:38

Last Modified:

06 Dec 2013 13:37

Publisher DOI:

10.1016/j.iac.2012.04.002

PubMed ID:

22560135

Web of Science ID:

000305038900004

URI:

https://boris.unibe.ch/id/eprint/15478 (FactScience: 222825)

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