Flow biocatalysis 101: design, development and applications

Benítez-Mateos, Ana I.; Contente, Martina L.; Roura Padrosa, David; Paradisi, Francesca (2021). Flow biocatalysis 101: design, development and applications. Reaction chemistry & engineering, 6(4), pp. 599-611. Royal Society of Chemistry 10.1039/D0RE00483A

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The integration of enzyme-catalyzed reactions in flow systems has been boosted during the last few years. Nowadays, biocatalysis is officially recognized as a tool to increase reaction specificity and sustainability, however applications are sometimes characterized by low productivity. A logical step to improve the performance of biocatalytic reactions is represented by the combination of enzymes and flow facilities. This tutorial review aims at introducing the key concepts of flow biocatalysis, guiding the reader through its advantages and highlighting the current trends in the field to encourage innovative applications of enzymes in flow reactors. Experimental cases are also presented and discussed as a troubleshooting guide for development of flow biocatalytic processes.

Item Type:

Journal Article (Review Article)

Division/Institute:

08 Faculty of Science > Department of Chemistry, Biochemistry and Pharmaceutical Sciences (DCBP)

UniBE Contributor:

Benitez Mateos, Ana Isabel; Contente, Martina Letizia; Roura Padrosa, David and Paradisi, Francesca

Subjects:

500 Science > 570 Life sciences; biology
500 Science > 540 Chemistry

ISSN:

2058-9883

Publisher:

Royal Society of Chemistry

Funders:

[4] Swiss National Science Foundation

Projects:

[UNSPECIFIED] 200021_192274/1

Language:

English

Submitter:

Francesca Paradisi

Date Deposited:

09 Apr 2021 09:04

Last Modified:

09 Apr 2021 09:13

Publisher DOI:

10.1039/D0RE00483A

BORIS DOI:

10.48350/155625

URI:

https://boris.unibe.ch/id/eprint/155625

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