Stricture prevention after extended circumferential endoscopic mucosal resection by injecting autologous keratinocytes in the sheep esophagus

Zuercher, Barbara F; George, Mercy; Escher, Anette; Piotet, Elsa; Ikonomidis, Christos; Andrejevic, Snezana Blant; Monnier, Philippe (2013). Stricture prevention after extended circumferential endoscopic mucosal resection by injecting autologous keratinocytes in the sheep esophagus. Surgical endoscopy and other interventional techniques, 27(3), pp. 1022-8. New York, N.Y.: Springer-Verlag 10.1007/s00464-012-2509-8

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During the past decades, endoscopic mucosal resection (EMR) has been developed to treat early intramucosal esophageal cancers and dysplastic Barrett's esophagus. The primary drawback of this method is severe postsurgical esophageal stricture formation. The purpose of this preclinical study was to assess strategies for prevention of this major complication by injecting autologous keratinocytes in the EMR mucosal defect in the sheep model.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Ear, Nose and Throat Disorders (ENT)

UniBE Contributor:

Zürcher, Barbara

ISSN:

0930-2794

Publisher:

Springer-Verlag

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:38

Last Modified:

23 Oct 2019 00:38

Publisher DOI:

10.1007/s00464-012-2509-8

PubMed ID:

22955900

Web of Science ID:

000315145500045

BORIS DOI:

10.7892/boris.15569

URI:

https://boris.unibe.ch/id/eprint/15569 (FactScience: 222948)

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