Case Report: Ambient Sensor Signals as Digital Biomarkers for Early Signs of Heart Failure Decompensation

Saner, Hugo; Schuetz, Narayan; Buluschek, Philipp; Du Pasquier, Guillaume; Ribaudo, Giuseppe; Urwyler, Prabitha; Nef, Tobias (2021). Case Report: Ambient Sensor Signals as Digital Biomarkers for Early Signs of Heart Failure Decompensation. Frontiers in cardiovascular medicine, 8, p. 617682. Frontiers 10.3389/fcvm.2021.617682

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Home monitoring systems are increasingly used to monitor seniors in their apartments for detection of emergency situations. More recently, multimodal ambient sensor systems are also used to monitor digital biomarkers to detect clinically relevant health problems over longer time periods. Clinical signs of HF decompensation including increase of heart rate and respiration rate, decreased physical activity, reduced gait speed, increasing toilet use at night and deterioration of sleep quality have a great potential to be detected by non-intrusive contactless ambient sensor systems and negative changes of these parameters may be used to prevent further deterioration and hospitalization for HF decompensation. This is to our knowledge the first report about the potential of an affordable, contactless, and unobtrusive ambient sensor system for the detection of early signs of HF decompensation based on data with prospective data acquisition and retrospective correlation of the data with clinical events in a 91 year old senior with a serious heart problem over 1 year. The ambient sensor system detected an increase of respiration rate, heart rate, toilet use at night, toss, and turns in bed and a decrease of physical activity weeks before the decompensation. In view of the rapidly increasing prevalence of HF and the related costs for the health care systems and the societies, the real potential of our approach should be evaluated in larger populations of HF patients.

Item Type:

Journal Article (Further Contribution)

Division/Institute:

04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurology
10 Strategic Research Centers > ARTORG Center for Biomedical Engineering Research
10 Strategic Research Centers > ARTORG Center for Biomedical Engineering Research > ARTORG Center - Gerontechnology and Rehabilitation

UniBE Contributor:

Saner, Hugo Ernst; Schütz, Narayan; Urwyler-Harischandra, Prabitha and Nef, Tobias

Subjects:

600 Technology > 610 Medicine & health
500 Science > 570 Life sciences; biology

ISSN:

2297-055X

Publisher:

Frontiers

Language:

English

Submitter:

Angela Amira Botros

Date Deposited:

06 May 2021 16:51

Last Modified:

09 May 2021 03:06

Publisher DOI:

10.3389/fcvm.2021.617682

PubMed ID:

33604357

BORIS DOI:

10.48350/156016

URI:

https://boris.unibe.ch/id/eprint/156016

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