Current hot potatoes in atrial fibrillation ablation

Roten, Laurent; Derval, N.; Pascale, P.; Scherr, D.; Komatsu, Y.; Shah, A.; Ramoul, K.; Denis, A.; Sacher, F.; Hocini, M.; Haissaguerre, M.; Jais, P. (2012). Current hot potatoes in atrial fibrillation ablation. Current cardiology reviews, 8(4), pp. 327-346. Sharjah: Bentham Science Publishers

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Atrial fibrillation (AF) ablation has evolved to the treatment of choice for patients with drug-resistant and symptomatic AF. Pulmonary vein isolation at the ostial or antral level usually is sufficient for treatment of true paroxysmal AF. For persistent AF ablation, drivers and perpetuators outside of the pulmonary veins are responsible for AF maintenance and have to be targeted to achieve satisfying arrhythmia-free success rate. Both complex fractionated atrial electrogram (CFAE) ablation and linear ablation are added to pulmonary vein isolation for persistent AF ablation. Nevertheless, ablation failure and necessity of repeat ablations are still frequent, especially after persistent AF ablation. Pulmonary vein reconduction is the main reason for arrhythmia recurrence after paroxysmal and to a lesser extent after persistent AF ablation. Failure of persistent AF ablation mostly is a consequence of inadequate trigger ablation, substrate modification or incompletely ablated or reconducting linear lesions. In this review we will discuss these points responsible for AF recurrence after ablation and review current possibilities on how to overcome these limitations.

Item Type:

Journal Article (Further Contribution)


04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiology

UniBE Contributor:

Roten, Laurent


600 Technology > 610 Medicine & health




Bentham Science Publishers




Factscience Import

Date Deposited:

04 Oct 2013 14:39

Last Modified:

29 Jan 2016 07:44

PubMed ID:


URI: (FactScience: 223015)

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