Osmotic diuresis due to urea as the cause of hypernatraemia in critically ill patients

Lindner, Gregor; Schwarz, Christoph; Funk, Georg-Christian (2012). Osmotic diuresis due to urea as the cause of hypernatraemia in critically ill patients. Nephrology, dialysis, transplantation, 27(3), pp. 962-7. Oxford: Oxford University Press 10.1093/ndt/gfr428

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Hypernatraemia is common in critically ill patients and has been shown to be an independent predictor of mortality. Osmotic urea diuresis can cause hypernatraemia due to significant water losses but is often not diagnosed. Free water clearance (FWC) and electrolyte free water clearance (EFWC) were proposed to quantify renal water handling. We aimed to (i) identify patients with hypernatraemia due to osmotic urea diuresis and (ii) investigate whether FWC and EFWC are helpful in identifying renal loss of free water.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of General Internal Medicine (DAIM) > Clinic of General Internal Medicine > Centre of Competence for General Internal Medicine

UniBE Contributor:

Lindner, Gregor

ISSN:

0931-0509

Publisher:

Oxford University Press

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:39

Last Modified:

31 Oct 2019 07:53

Publisher DOI:

10.1093/ndt/gfr428

PubMed ID:

21810766

Web of Science ID:

000301907200018

BORIS DOI:

10.7892/boris.15684

URI:

https://boris.unibe.ch/id/eprint/15684 (FactScience: 223106)

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