Augur: a bioinformatics toolkit for phylogenetic analyses of human pathogens.

Huddleston, John; Hadfield, James; Sibley, Thomas R; Lee, Jover; Fay, Kairsten; Ilcisin, Misja; Harkins, Elias; Bedford, Trevor; Neher, Richard A; Hodcroft, Emma B. (2021). Augur: a bioinformatics toolkit for phylogenetic analyses of human pathogens. Journal of Open Source Software, 6(57), p. 2906. Open Journals 10.21105/joss.02906

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The analysis of human pathogens requires a diverse collection of bioinformatics tools. These tools include standard genomic and phylogenetic software and custom software developed to handle the relatively numerous and short genomes of viruses and bacteria. Researchers increasingly depend on the outputs of these tools to infer transmission dynamics of human diseases and make actionable recommendations to public health officials (Black et al., 2020; Gardy et al., 2015). In order to enable real-time analyses of pathogen evolution, bioinformatics tools must scale rapidly with the number of samples and be flexible enough to adapt to a variety of questions and organisms. To meet these needs, we developed Augur, a bioinformatics toolkit designed for phylogenetic analyses of human pathogens.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Social and Preventive Medicine (ISPM)

UniBE Contributor:

Hodcroft, Emma Britt

Subjects:

600 Technology > 610 Medicine & health
300 Social sciences, sociology & anthropology > 360 Social problems & social services

ISSN:

2475-9066

Publisher:

Open Journals

Language:

English

Submitter:

Andrea Flükiger-Flückiger

Date Deposited:

07 Jul 2021 23:14

Last Modified:

21 Jun 2023 15:57

Publisher DOI:

10.21105/joss.02906

PubMed ID:

34189396

BORIS DOI:

10.48350/157387

URI:

https://boris.unibe.ch/id/eprint/157387

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