Asimakidou, Evridiki; Abut, Pablo Alvarez; Raabe, Andreas; Seidel, Kathleen (2021). Motor Evoked Potential Warning Criteria in Supratentorial Surgery: A Scoping Review. Cancers, 13(11) MDPI AG 10.3390/cancers13112803
|
Text
cancers-13-02803-v4.pdf - Published Version Available under License Creative Commons: Attribution (CC-BY). Download (2MB) | Preview |
During intraoperative monitoring of motor evoked potentials (MEP), heterogeneity across studies in terms of study populations, intraoperative settings, applied warning criteria, and outcome reporting exists. A scoping review of MEP warning criteria in supratentorial surgery was conducted in accordance with the Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR). Sixty-eight studies fulfilled the eligibility criteria. The most commonly used alarm criteria were MEP signal loss, which was always a major warning sign, followed by amplitude reduction and threshold elevation. Irreversible MEP alterations were associated with a higher number of transient and persisting motor deficits compared with the reversible changes. In almost all studies, specificity and Negative Predictive Value (NPV) were high, while in most of them, sensitivity and Positive Predictive Value (PPV) were rather low or modest. Thus, the absence of an irreversible alteration may reassure the neurosurgeon that the patient will not suffer a motor deficit in the short-term and long-term follow-up. Further, MEPs perform well as surrogate markers, and reversible MEP deteriorations after successful intervention indicate motor function preservation postoperatively. However, in future studies, a consensus regarding the definitions of MEP alteration, critical duration of alterations, and outcome reporting should be determined.
Item Type: |
Journal Article (Review Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurosurgery |
UniBE Contributor: |
Raabe, Andreas, Seidel, Kathleen |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
2072-6694 |
Publisher: |
MDPI AG |
Language: |
English |
Submitter: |
Nicole Söll |
Date Deposited: |
14 Jul 2021 13:54 |
Last Modified: |
05 Dec 2022 15:52 |
Publisher DOI: |
10.3390/cancers13112803 |
PubMed ID: |
34199853 |
Uncontrolled Keywords: |
aneurysm clipping glioma surgery intraoperative monitoring intraoperative neurophysiology motor deficit motor evoked potential warning criteria |
BORIS DOI: |
10.48350/157493 |
URI: |
https://boris.unibe.ch/id/eprint/157493 |
Actions (login required)
 |
Edit item |