Signorell, J; Hunziker, T; Martinelli, M; Koestner, S C; Mohacsi, P J (2010). Recurrent non-melanoma skin cancer: remission of field cancerization after conversion from calcineurin inhibitor- to proliferation signal inhibitor-based immunosuppression in a cardiac transplant recipient. Transplantation proceedings, 42(9), pp. 3871-5. New York, N.Y.: Elsevier 10.1016/j.transproceed.2010.07.090
Full text not available from this repository. (Request a copy)Non-melanoma skin cancers (NMSCs) are the most common malignancies after solid organ transplantation. Their incidence increases with time after transplantation. Calcineurin-inhibitors (CNIs) and azathioprine are known as skin neoplasia-initiating and -enhancing immunosuppressants. In contrast, increasing clinical experience suggests a relevant antiproliferative effect of mammalian target of rapamycin inhibitors, also named proliferation signal inhibitors (PSIs). We report the case of a cardiac allograft recipient with an impressive and consolidated reduction of recurrent NMSC, observed after conversion from CNI-therapy to a PSI-based protocol.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiology 04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Dermatology |
UniBE Contributor: |
Signorell, Jan, Hunziker, Thomas, Martinelli, Michele, Köstner, Simon Charles, Mohacsi, Paul |
ISSN: |
0041-1345 |
Publisher: |
Elsevier |
Language: |
English |
Submitter: |
Factscience Import |
Date Deposited: |
04 Oct 2013 14:10 |
Last Modified: |
05 Dec 2022 14:01 |
Publisher DOI: |
10.1016/j.transproceed.2010.07.090 |
PubMed ID: |
21094874 |
Web of Science ID: |
000284969800097 |
URI: |
https://boris.unibe.ch/id/eprint/1576 (FactScience: 203352) |
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