[Antibacterial Prophylaxis in Children and Adolescents Undergoing Therapy for Cancer - Statement of the Society of Pediatric Oncology and Hematology (GPOH) and of the German Society for Pediatric Infectious Diseases (DGPI) on Two Current International Guidelines].

Lehrnbecher, Thomas; Simon, Arne; Laws, Hans-Jürgen; Agyeman, Philipp KA; Ammann, Roland A; Attarbaschi, Andishe; Berger, Christoph; Bochennek, Konrad; Neubert, Jennifer; Poyer, Fiona; Scheler, Max; Strenger, Volker; Vieth, Simon; Zoellner, Stefan; Groll, Andreas H (2021). [Antibacterial Prophylaxis in Children and Adolescents Undergoing Therapy for Cancer - Statement of the Society of Pediatric Oncology and Hematology (GPOH) and of the German Society for Pediatric Infectious Diseases (DGPI) on Two Current International Guidelines]. Klinische Pädiatrie, 233(3), pp. 101-106. Thieme 10.1055/a-1443-6576

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Immunocompromised children and adolescents receiving treatment for cancer have an increased risk for potentially life-threatening infectious complications such as blood stream infections with Gram-positive and Gram-negative pathogens. Therefore, several centers for Pediatric Hematology and Oncology administer antibacterial prophylaxis to these patients to lower morbidity and mortality. Two pediatric specific guidelines on antibacterial prophylaxis were recently published. One of these guidelines was drawn up by an international group of pediatric experts of Europe, North and South America and Australia. The other guideline was prepared by an European group convened at the Eighth European Conference on Infections in Leukaemia (ECIL-8). In this review article, the working groups "Infections" of the Society of Pediatric Oncology and Hematology (GPOH) and "Fever in the neutropenic host" of the German Society for Pediatric Infectious Diseases" (DGPI) summarize the available data from randomized studies, systematic reviews and meta-analyses on antibacterial prophylaxis as well of current data on the emergence of resistance and discuss methodological aspects and the recommendations of the two guidelines.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Paediatric Medicine
04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Paediatric Medicine > Paediatric Infectiology

UniBE Contributor:

Agyeman, Philipp Kwame Abayie and Ammann, Roland

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1439-3824

Publisher:

Thieme

Language:

German

Submitter:

Christoph Aebi

Date Deposited:

09 Aug 2021 15:59

Last Modified:

09 Aug 2021 15:59

Publisher DOI:

10.1055/a-1443-6576

PubMed ID:

33971688

URI:

https://boris.unibe.ch/id/eprint/157806

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