Population genetic analysis of 12 X-chromosomal STRs in a Swiss sample.

Bottinelli, Michel; Gouy, Alexandre; Utz, Silvia; Zieger, Martin (2022). Population genetic analysis of 12 X-chromosomal STRs in a Swiss sample. International journal of legal medicine, 136(2), pp. 561-563. Springer 10.1007/s00414-021-02684-y

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X-chromosomal STRs are a powerful tool to assess a broad variety of complex kinship scenarios. We introduce herewith the first Swiss X-STR dataset based on 1198 individuals (592 female, 606 male), characterized with the Qiagen Investigator® Argus X-12 QS multiplex kit. Anomalous allele patterns, allele and haplotype frequencies, and forensic and population genetic parameters are presented. We detected linkage disequilibrium within three out of the four designated linkage groups and no apparent intra-national population substructure. We compared the dataset to a global panel of X-STR datasets and it fits well in the European context, as expected.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Service Sector > Institute of Legal Medicine
04 Faculty of Medicine > Service Sector > Institute of Legal Medicine > Forensic Molecular Biology

UniBE Contributor:

Utz, Silvia, Zieger, Martin

Subjects:

600 Technology > 610 Medicine & health
500 Science > 570 Life sciences; biology

ISSN:

0937-9827

Publisher:

Springer

Language:

English

Submitter:

Antoinette Angehrn

Date Deposited:

16 Sep 2021 10:03

Last Modified:

05 Dec 2022 15:53

Publisher DOI:

10.1007/s00414-021-02684-y

PubMed ID:

34420081

Uncontrolled Keywords:

Forensics Kinship Population data Switzerland X-STR

BORIS DOI:

10.48350/159009

URI:

https://boris.unibe.ch/id/eprint/159009

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