Spatial variations in Leishmaniasis: A biogeographic approach to mapping the distribution of Leishmania species.

Jagadesh, Soushieta; Combe, Marine; Ginouvès, Marine; Simon, Stéphane; Prévot, Ghislaine; Couppié, Pierre; Nacher, Mathieu; Gozlan, Rodolphe Elie (2021). Spatial variations in Leishmaniasis: A biogeographic approach to mapping the distribution of Leishmania species. One health, 13, p. 100307. Elsevier 10.1016/j.onehlt.2021.100307

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Cutaneous Leishmaniasis (CL) is the most prevalent form of Leishmaniasis and is widely endemic in the Americas. Several species of Leishmania are responsible for CL, a severely neglected tropical disease and the treatment of CL vary according to the different species of Leishmania. We proposed to map the distribution of the Leishmania species reported in French Guiana (FG) using a biogeographic approach based on environmental predictors. We also measured species endemism i.e., the uniqueness of species to a defined geographic location. Our results show that the distribution patterns varied between Leishmania spp. and were spatially dependent on climatic covariates. The species distribution modelling of the eco-epidemiological spatial patterns of Leishmania spp. is the first to measure endemism based on bioclimatic factors in FG. The study also emphasizes the impact of tree cover loss and climate on the increasing distribution of L. (Viannia) braziliensis in the most anthropized regions. Detection of high-risk regions for the different between Leishmania spp. is essential for monitoring and active surveillance of the vector. As climate plays a major role in the spatial distribution of the vector and reservoir and the survival of the pathogen, climatic covariates should be included in the analysis and mapping of vector-borne diseases. This study underscores the significance of local land management and the urgency of considering the impact of climate change in the development of vector-borne disease management strategies at the global scale.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Social and Preventive Medicine (ISPM)

UniBE Contributor:

Jagadesh, Soushieta

Subjects:

600 Technology > 610 Medicine & health
300 Social sciences, sociology & anthropology > 360 Social problems & social services

ISSN:

2352-7714

Publisher:

Elsevier

Language:

English

Submitter:

Andrea Flükiger-Flückiger

Date Deposited:

07 Sep 2021 16:37

Last Modified:

03 Jan 2023 11:18

Publisher DOI:

10.1016/j.onehlt.2021.100307

PubMed ID:

34430698

Uncontrolled Keywords:

Biogeography Cutaneous leishmaniasis Deforestation One health Stacked species distribution modelling Zoonosis

BORIS DOI:

10.48350/159132

URI:

https://boris.unibe.ch/id/eprint/159132

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