Quantification of Liver Fat Content with Ultrasound: A WFUMB Position Paper.

Ferraioli, Giovanna; Berzigotti, Annalisa; Barr, Richard G; Choi, Byung I; Cui, Xin Wu; Dong, Yi; Gilja, Odd Helge; Lee, Jae Young; Lee, Dong Ho; Moriyasu, Fuminori; Piscaglia, Fabio; Sugimoto, Katsutoshi; Wong, Grace Lai-Hung; Wong, Vincent Wai-Sun; Dietrich, Christoph F (2021). Quantification of Liver Fat Content with Ultrasound: A WFUMB Position Paper. Ultrasound in medicine & biology, 47(10), pp. 2803-2820. Elsevier 10.1016/j.ultrasmedbio.2021.06.002

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New ultrasound methods that can be used to quantitatively assess liver fat content have recently been developed. These quantitative ultrasound (QUS) methods are based on the analysis of radiofrequency echoes detected by the transducer, allowing calculation of parameters for quantifying the fat in the liver. In this position paper, after a section dedicated to the importance of quantifying liver steatosis in patients with non-alcoholic fatty liver disease and another section dedicated to the assessment of liver fat with magnetic resonance, the current clinical studies performed using QUS are summarized. These new methods include spectral-based techniques and techniques based on envelope statistics. The spectral-based techniques that have been used in clinical studies are those estimating the attenuation coefficient and those estimating the backscatter coefficient. Clinical studies that have used tools based on the envelope statistics of the backscattered ultrasound are those performed by using the acoustic structure quantification or other parameters derived from it, such as the normalized local variance, and that performed by estimating the speed of sound. Experts' opinions are reported.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Hepatologie
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Hepatologie

04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine > Hepatology

UniBE Contributor:

Berzigotti, Annalisa

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0301-5629

Publisher:

Elsevier

Language:

English

Submitter:

Rahel Fuhrer

Date Deposited:

13 Oct 2021 10:39

Last Modified:

05 Dec 2022 15:53

Publisher DOI:

10.1016/j.ultrasmedbio.2021.06.002

PubMed ID:

34284932

Uncontrolled Keywords:

Attenuation coefficient Backscatter Controlled attenuation parameter Dispersion Non-alcoholic fatty liver disease Non-alcoholic steatohepatitis Quantitative ultrasound Speed of sound

BORIS DOI:

10.48350/159664

URI:

https://boris.unibe.ch/id/eprint/159664

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