Advancing a temporal framework for understanding the biology of nonsuicidal self- injury: An expert review

Kaess, Michael; Hooley, Jill M.; Klimes-Dougan, Bonnie; Koenig, Julian; Plener, Paul L.; Reichl, Corinna; Robinson, Kealagh; Schmahl, Christian; Sicorello, Maurizio; Westlund Schreiner, Mindy; Cullen, Kathryn R. (2021). Advancing a temporal framework for understanding the biology of nonsuicidal self- injury: An expert review. Neuroscience & biobehavioral reviews, 130, pp. 228-239. Elsevier 10.1016/j.neubiorev.2021.08.022

Preview

Text 1-s2.0-S0149763421003717-main.pdf - Published Version Available under License Creative Commons: Attribution (CC-BY). Download (1MB) | Preview

Nonsuicidal self-injury (NSSI) is a serious clinical problem, particularly for adolescents and young adults. NSSI is a complex behavior that emerges through the intersecting effects of social, psychological, and biological mechanisms. Although the social and psychological contributions to risk for developing NSSI are relatively well understood and have guided the development of effective psychosocial treatments for self-injury, the biological mechanisms underlying NSSI have just begun to come to light. To evaluate and categorize the biological research conducted on the topic of NSSI, we propose a model that distinguishes between trait and state markers. According to this model, risk factors and mechanisms involved in NSSI can be distinguished into both trait and state factors. We review the existing evidence on distal biological traits (predictors) of NSSI, proximal biological traits (correlates) of NSSI, and biological states directly preceding or following NSSI. We conclude by providing recommendations for future research on the neurobiology of NSSI.

Interest & Impact

Downloads

245 since deposited on 15 Oct 2021
85 in the past 12 months

Citations

5 Citations in Web of Science ®
6 Citations in Scopus

Search

in Google Scholar™

Services

Actions (login required)

Edit item

Actions (login required)

Edit item