Christensen, Jeppe Brage; Togno, Michele; Nesteruk, Konrad Pawel; Psoroulas, Serena; Meer, David; Weber, Damien Charles; Lomax, Tony; Yukihara, Eduardo G; Safai, Sairos (2021). Al2O3:C optically stimulated luminescence dosimeters (OSLDs) for ultra-high dose rate proton dosimetry. Physics in medicine and biology, 66(8) Institute of Physics Publishing IOP 10.1088/1361-6560/abe554
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Christensen_2021_Phys._Med._Biol._66_085003.pdf - Published Version Available under License Creative Commons: Attribution (CC-BY). Download (2MB) | Preview |
The response of Al2O3:C optically stimulated luminescence detectors (OSLDs) was investigated in a 250 MeV pencil proton beam. The OSLD response was mapped for a wide range of average dose rates up to 9000 Gy s-1, corresponding to a ∼150 kGy s-1instantaneous dose rate in each pulse. Two setups for ultra-high dose rate (FLASH) experiments are presented, which enable OSLDs or biological samples to be irradiated in either water-filled vials or cylinders. The OSLDs were found to be dose rate independent for all dose rates, with an average deviation <1% relative to the nominal dose for average dose rates of (1-1000) Gy s-1when irradiated in the two setups. A third setup for irradiations in a 9000 Gy s-1pencil beam is presented, where OSLDs are distributed in a 3 × 4 grid. Calculations of the signal averaging of the beam over the OSLDs were in agreement with the measured response at 9000 Gy s-1. Furthermore, a new method was presented to extract the beam spot size of narrow pencil beams, which is in agreement within a standard deviation with results derived from radiochromic films. The Al2O3:C OSLDs were found applicable to support radiobiological experiments in proton beams at ultra-high dose rates.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Radiation Oncology |
UniBE Contributor: |
Weber, Damien Charles |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
0031-9155 |
Publisher: |
Institute of Physics Publishing IOP |
Language: |
English |
Submitter: |
Beatrice Scheidegger |
Date Deposited: |
09 Nov 2021 15:31 |
Last Modified: |
05 Dec 2022 15:53 |
Publisher DOI: |
10.1088/1361-6560/abe554 |
PubMed ID: |
33571973 |
Uncontrolled Keywords: |
Al2O3:C FLASH optically stimulated luminescence proton dosimetry ultra-high dose rate |
BORIS DOI: |
10.48350/160333 |
URI: |
https://boris.unibe.ch/id/eprint/160333 |
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