Büsching, Gilbert; Zhang, Zhongxing; Schmid, Jean-Paul; Sigrist, Thomas; Khatami, Ramin (2021). Effectiveness of Pulmonary Rehabilitation in Severe and Critically Ill COVID-19 Patients: A Controlled Study. International journal of environmental research and public health, 18(17) MDPI 10.3390/ijerph18178956
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BACKGROUND
Severe and critically ill COVID-19 patients frequently need pulmonary rehabilitation (PR) after hospitalization. However, little is known about the effectiveness of PR in COVID-19 patients.
METHODS
We compared the performances in the six-min walk test (6MWT), chronic respiratory questionnaire (CRQ), and Functional Independence Measure (FIM) from inpatient PR between 51 COVID-19 patients and 51 other patients with common pneumonia. We used multivariate linear regression controlled for baseline values at entrance, age, sex, and cumulative illness rating scale. The odds ratios (ORs) of non-improvement/improvement in 6MWT (>30-m) and CRQ (>10-point) at discharge were compared between the two groups (Fisher's exact test).
RESULTS
The two groups had similar improvements in 6MWT and CRQ, but the COVID-19 group achieved a 4-point higher FIM (p-value = 0.004). The OR of non-improvement/improvement in 6MWT was 0.30 (p-value = 0.13) between COVID-19 and controls; however, the odds of non-improvement in CRQ tended to be 3.02 times higher (p-value = 0.075) in COVID-19 patients. Severe and critical COVID-19 patients had similar rehabilitation outcomes.
CONCLUSIONS
Inpatient PR can effectively improve physical functions and life quality in COVID-19 patients, irrespective of disease severity. Whether the relatively low gains in CRQ is an indicator of chronic disease development in COVID-19 patients needs further studies.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurology |
UniBE Contributor: |
Khatami, Ramin |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1660-4601 |
Publisher: |
MDPI |
Language: |
English |
Submitter: |
Chantal Kottler |
Date Deposited: |
22 Nov 2021 14:35 |
Last Modified: |
05 Dec 2022 15:54 |
Publisher DOI: |
10.3390/ijerph18178956 |
PubMed ID: |
34501549 |
Uncontrolled Keywords: |
6-MWT COVID-19 CRQ FIM pneumonia pulmonary rehabilitation |
BORIS DOI: |
10.48350/160816 |
URI: |
https://boris.unibe.ch/id/eprint/160816 |
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