Shelan, Mohamed; Aebersold, Daniel M.; Albrecht, Clemens; Böhmer, Dirk; Flentje, Michael; Ganswindt, Ute; Höcht, Stefan; Hölscher, Tobias; Müller, Arndt-Christian; Niehoff, Peter; Pinkawa, Michael; Schmidt-Hegemann, Nina-Sophie; Sedlmayer, Felix; Wolf, Frank; Zamboglou, Constantinos; Zips, Daniel; Wiegel, Thomas; Ghadjar, Pirus (2021). Moderately hypofractionated radiotherapy as definitive treatment for localized prostate cancer: Pattern of practice in German-speaking countries : A survey of the Prostate Cancer Expert Panel of the German Society of Radiation Oncology (DEGRO) and the Working Party on Radiation Oncology of the German Cancer Society (DKG-ARO). Strahlentherapie und Onkologie, 197(11), pp. 993-1000. Springer 10.1007/s00066-021-01820-2
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PURPOSE
Various randomized phase III clinical trials have compared moderately hypofractionated to normofractionated radiotherapy (RT). These modalities showed similar effectiveness without major differences in toxicity. This project was conducted by the Prostate Cancer Expert Panel of the German Society of Radiation Oncology (DEGRO) and the Working Party on Radiation Oncology of the German Cancer Society. We aimed to investigate expert opinions on the use of moderately hypofractionated RT as a definitive treatment for localized prostate cancer in German-speaking countries.
METHODS
A 25-item, web-based questionnaire on moderate-hypofractionation RT was prepared by an internal committee. The experts of the DEGRO were asked to complete the questionnaire.
RESULTS
Fourteen active members of DEGRO completed the questionnaire. The questions described indications for selecting patients eligible to receive moderate hypofractionation based on clinical and pathological factors such as age, urinary symptoms, and risk-group. The questions also collected information on the technical aspects of selection criteria, including the definition of a clinical target volume, the use of imaging, protocols for bladder and rectal filling, the choice of a fractionation schedule, and the use of image guidance. Moreover, the questionnaire collected information on post-treatment surveillance after applying moderately hypofractionated RT.
CONCLUSION
Although opinions varied on the use of moderate-hypofractionation RT, the current survey reflected broad agreement on the notion that moderately hypofractionated RT could be considered a standard treatment for localized prostate cancer in German-speaking countries.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Radiation Oncology |
UniBE Contributor: |
Shelan, Mohamed, Aebersold, Daniel Matthias, Ghadjar, Pirus |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1439-099X |
Publisher: |
Springer |
Language: |
English |
Submitter: |
Beatrice Scheidegger |
Date Deposited: |
06 Dec 2021 09:55 |
Last Modified: |
05 Dec 2022 15:54 |
Publisher DOI: |
10.1007/s00066-021-01820-2 |
PubMed ID: |
34463814 |
Uncontrolled Keywords: |
Guidelines Hypofractionation Prostate cancer Radiotherapy Survey |
BORIS DOI: |
10.48350/161240 |
URI: |
https://boris.unibe.ch/id/eprint/161240 |
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