Harrell, Carl Randall; Djonov, Valentin; Volarevic, Vladislav (2021). The Cross-Talk between Mesenchymal Stem Cells and Immune Cells in Tissue Repair and Regeneration. International journal of molecular sciences, 22(5) MDPI 10.3390/ijms22052472
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Mesenchymal stem cells (MSCs) are self-renewable, rapidly proliferating, multipotent stem cells which reside in almost all post-natal tissues. MSCs possess potent immunoregulatory properties and, in juxtacrine and paracrine manner, modulate phenotype and function of all immune cells that participate in tissue repair and regeneration. Additionally, MSCs produce various pro-angiogenic factors and promote neo-vascularization in healing tissues, contributing to their enhanced repair and regeneration. In this review article, we summarized current knowledge about molecular mechanisms that regulate the crosstalk between MSCs and immune cells in tissue repair and regeneration.
Item Type: |
Journal Article (Review Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Anatomy 04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Anatomy > Topographical and Clinical Anatomy |
UniBE Contributor: |
Djonov, Valentin Georgiev |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1422-0067 |
Publisher: |
MDPI |
Language: |
English |
Submitter: |
David Christian Haberthür |
Date Deposited: |
30 Nov 2021 16:05 |
Last Modified: |
05 Dec 2022 15:54 |
Publisher DOI: |
10.3390/ijms22052472 |
PubMed ID: |
33804369 |
BORIS DOI: |
10.48350/161286 |
URI: |
https://boris.unibe.ch/id/eprint/161286 |
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