Impact of a structured patient education programme on early diagnosis of prosthetic pulmonary valve endocarditis.

Babic, Daniela; Hämmerli, Ramona; Santos Lopes, Bruno; Attenhofer Jost, Christine; Tobler, Daniel; Schwerzmann, Markus; Hasse, Barbara; Bonassin Tempesta, Francesca; Greutmann, Matthias (2021). Impact of a structured patient education programme on early diagnosis of prosthetic pulmonary valve endocarditis. (In Press). Cardiology in the young, pp. 1-6. Cambridge University Press 10.1017/S1047951121004510

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BACKGROUND

Infective endocarditis is a major threat after prosthetic pulmonary valve replacement. Early diagnosis may improve outcomes.

METHODS

A structured patient education programme for prevention and early diagnosis of infective endocarditis was developed at our institution since 2016. Time delay between onset of symptoms of prosthetic pulmonary valve endocarditis and its diagnosis (defined as initiation of appropriate high-dose intravenous antibiotic treatment) was compared for patients presenting before (cohort 1) and after (cohort 2) initiation of the patient education programme.

RESULTS

Between 2008-2019, 26 patients (median age 24.9, range: 16.8-62.0 years, 73% male) were diagnosed with prosthetic pulmonary valve endocarditis, 13 patients (cohort 1) before (1.7 cases/year) and 13 patients (cohort 2) after June 2016 (3.7 cases/year). There were no differences in baseline characteristics or clinical presentation between the study cohorts. Overall, the median delay between onset of symptoms and diagnosis of infective endocarditis was 6 days (range: 0-133 days) with a significantly longer delay among patients in cohort 1, compared to cohort 2 (25 days, range: 5-133 days versus 3 days, range: 0-13 days, p < 0.0001). A delay of >7 days was documented in 11/13 patients (85%) in cohort 1 as compared to 1/13 (8%) in cohort 2 (p < 0.001). Need for urgent valve replacement or permanent deterioration of prosthetic valve function was higher in cohort 1, compared to cohort 2 (11/13, 85% versus 5/13, 39%; p = 0.041).

CONCLUSIONS

Prosthetic pulmonary valve endocarditis is increasingly recognised. A structured patient education programme may improve early diagnosis and clinical outcomes.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiology

UniBE Contributor:

Schwerzmann, Markus

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1047-9511

Publisher:

Cambridge University Press

Language:

English

Submitter:

Markus Schwerzmann

Date Deposited:

08 Feb 2022 15:27

Last Modified:

08 Feb 2022 15:27

Publisher DOI:

10.1017/S1047951121004510

PubMed ID:

34753524

Uncontrolled Keywords:

Pulmonary valve replacement Ross operation infective endocarditis tetralogy of Fallot

URI:

https://boris.unibe.ch/id/eprint/161676

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