Garaiman, Alexandru; Mihai, Carina; Dobrota, Rucsandra; Jordan, Suzana; Maurer, Britta; Flemming, Jan; Distler, Oliver; Becker, Mike Oliver (2021). The Hospital Anxiety and Depression Scale in patients with systemic sclerosis: a psychometric and factor analysis in a monocentric cohort. Clinical and experimental rheumatology, 39 Suppl 131(4), S34-S42. Pacini editore
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OBJECTIVES
To evaluate the feasibility, validity, reliability, and responsiveness of the Hospital Anxiety and Depression Scale (HADS) and to analyse its model structure in patients with systemic sclerosis (SSc).
METHODS
In this study, 316 SSc patients were included; of these, 159 participated in the responsiveness analysis. Psychometric properties were tested in analogy to the Outcome Measures in Rheumatology (OMERACT) filter and an exploratory and confirmatory factor analysis was performed to examine the structure of HADS.
RESULTS
The HADS showed adequate feasibility, validity, reliability, and responsiveness to clinically relevant worsening of the disease. For our population of SSc patients, the HADS model with two sub-scales, HADS-A and HADS-D, and a general scale HADS-S, measuring anxiety, depression, and distress, respectively, was most appropriate. The rates of anxiety, depression, mixed anxiety-depressive disorder (MADD) and distress identified by HADS were 32.2%, 25.9%, 18.5%, and 49.5%, respectively, in our cohort.
CONCLUSIONS
The psychometric properties of the HADS make it useful for screening in SSc, where anxiety, depression, MADD, and distress represent a significant burden to patients.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Rheumatology, Clinical Immunology and Allergology |
UniBE Contributor: |
Maurer, Britta |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
0392-856X |
Publisher: |
Pacini editore |
Language: |
English |
Submitter: |
Brigitte Isenschmid |
Date Deposited: |
19 Jan 2022 10:55 |
Last Modified: |
05 Dec 2022 15:55 |
PubMed ID: |
33886453 |
BORIS DOI: |
10.48350/161845 |
URI: |
https://boris.unibe.ch/id/eprint/161845 |
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