Noncoding RNAs: biology and applications-a Keystone Symposia report.

Cable, Jennifer; Heard, Edith; Hirose, Tetsuro; Prasanth, Kannanganattu V; Chen, Ling-Ling; Henninger, Jonathan E; Quinodoz, Sofia A; Spector, David L; Diermeier, Sarah D; Porman, Allison M; Kumar, Dhiraj; Feinberg, Mark W; Shen, Xiaohua; Unfried, Juan Pablo; Johnson, Rory; Chen, Chun-Kan; Wilusz, Jeremy E; Lempradl, Adelheid; McGeary, Sean E; Wahba, Lamia; ... (2021). Noncoding RNAs: biology and applications-a Keystone Symposia report. Annals of the New York Academy of Sciences, 1506(1), pp. 118-141. New York Academy of Sciences 10.1111/nyas.14713

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The human transcriptome contains many types of noncoding RNAs, which rival the number of protein-coding species. From long noncoding RNAs (lncRNAs) that are over 200 nucleotides long to piwi-interacting RNAs (piRNAs) of only 20 nucleotides, noncoding RNAs play important roles in regulating transcription, epigenetic modifications, translation, and cell signaling. Roles for noncoding RNAs in disease mechanisms are also being uncovered, and several species have been identified as potential drug targets. On May 11-14, 2021, the Keystone eSymposium "Noncoding RNAs: Biology and Applications" brought together researchers working in RNA biology, structure, and technologies to accelerate both the understanding of RNA basic biology and the translation of those findings into clinical applications.

Item Type:

Journal Article (Original Article)


04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Medical Oncology
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR)

UniBE Contributor:

Johnson, Rory Baldwin


600 Technology > 610 Medicine & health




New York Academy of Sciences




Rebeka Gerber

Date Deposited:

29 Dec 2021 11:51

Last Modified:

05 Dec 2022 15:55

Publisher DOI:


PubMed ID:


Uncontrolled Keywords:

Xist circRNA lncRNA noncoding RNA nuclear condensate phase transition piRNA transcription




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