Gagesch, M.; Chocano-Bedoya, P. O.; Abderhalden, L.A.; Freystaetter, G.; Sadlon, A.; Kanis, J.A.; Kressig, R.W.; Guyonnet, S.; DaSilva, J.A.P.; Felsenberg, D.; Rizzoli, R.; Blauth, M.; Orav, E.J.; Egli, A.; Bischoff-Ferrari, H.A. (2021). Prevalence of Physical Frailty: Results from the DO-HEALTH Study (In Press). Journal of Frailty & Aging Springer 10.14283/jfa.2021.18
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Background
Frailty is a geriatric syndrome associated with multiple negative health outcomes. However, its prevalence varies by population and instrument used. We investigated frailty and pre-frailty prevalence by 5 instruments in community-dwelling older adults enrolled to a randomized-controlled trial in 5 European countries.
Methods
Cross-sectional baseline analysis in 2,144 DO-HEALTH participants recruited from Switzerland, Austria, France, Germany, and Portugal with complete data for frailty. Frailty status was assessed by the Physical Frailty Phenotype [PFP], SOF-Frailty Index [SOF-FI], FRAIL-Scale, SHARE-Frailty Instrument [SHARE-FI], and a modified SHARE-FI, and compared by country, age, and gender. Logistic regression was used to determine relevant factors associated with frailty and pre-frailty.
Results
Mean age was 74.9 (±4.4) years, 61.6% were women. Based on the PFP, overall frailty and pre-frailty prevalence was 3.0% and 43.0%. By country, frailty prevalence was highest in Portugal (13.7%) and lowest in Austria (0%), and pre-frailty prevalence was highest in Portugal (57.3%) and lowest in Germany (37.1%). By instrument and overall, frailty and pre-frailty prevalence was highest based on SHARE-FI (7.0% / 43.7%) and lowest based on SOF-FI (1.0% / 25.9%). Frailty associated factors were residing in Coimbra (Portugal) [OR 12.0, CI 5.30–27.21], age above 75 years [OR 2.0, CI 1.17–3.45], and female gender [OR 2.8, CI 1.48–5.44]. The same three factors predicted pre-frailty.
Conclusions
Among relatively healthy adults age 70 and older enroled to DO-HEALTH, prevalence of frailty and pre-frailty differed significantly by instrument, country, gender, and age. Among instruments, the highest prevalence of frailty and pre-frailty was documented by the SHARE-FI and the lowest by the SOF-FI.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
04 Faculty of Medicine > Medical Education > Institute of General Practice and Primary Care (BIHAM) |
UniBE Contributor: |
Chocano Bedoya, Patricia Orializ |
Subjects: |
600 Technology > 610 Medicine & health 300 Social sciences, sociology & anthropology > 360 Social problems & social services |
ISSN: |
2273-4309 |
Publisher: |
Springer |
Language: |
English |
Submitter: |
Doris Kopp Heim |
Date Deposited: |
09 Dec 2021 09:45 |
Last Modified: |
05 Dec 2022 15:56 |
Publisher DOI: |
10.14283/jfa.2021.18 |
Additional Information: |
Open Access funding provided by University of Zurich. |
BORIS DOI: |
10.48350/162114 |
URI: |
https://boris.unibe.ch/id/eprint/162114 |
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