Mink van der Molen, Aebele B; van Breugel, Johanna M M; Janssen, Nard G; Admiraal, Ronald J C; van Adrichem, Leon N A; Bierenbroodspot, Frank; Bittermann, Dirk; van den Boogaard, Marie-José H; Broos, Pieter H; Dijkstra-Putkamer, Janet J M; van Gemert-Schriks, Martine C M; Kortlever, Andrea L J; Mouës-Vink, Chantal M; Swanenburg de Veye, Henriette F N; van Tol-Verbeek, Nanouk; Vermeij-Keers, Christl; de Wilde, Hester; Kuijpers-Jagtman, Anne Marie; Kuijpers-Jagtman, Anne Marie (2021). Clinical Practice Guidelines on the Treatment of Patients with Cleft Lip, Alveolus, and Palate: An Executive Summary. Journal of clinical medicine, 10(21) MDPI 10.3390/jcm10214813
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Significant treatment variation exists in the Netherlands between teams treating patients with cleft lip, alveolus, and/or palate, resulting in a confusing and undesirable situation for patients, parents, and practitioners. Therefore, to optimize cleft care, clinical practice guidelines (CPGs) were developed. The aim of this report is to describe CPG development, share the main recommendations, and indicate knowledge gaps regarding cleft care. Together with patients and parents, a multidisciplinary working group of representatives from all relevant disciplines assisted by two experienced epidemiologists identified the topics to be addressed in the CPGs. Searching the Medline, Embase, and Cochrane Library databases identified 5157 articles, 60 of which remained after applying inclusion and exclusion criteria. We rated the quality of the evidence from moderate to very low. The working group formulated 71 recommendations regarding genetic testing, feeding, lip and palate closure, hearing, hypernasality, bone grafting, orthodontics, psychosocial guidance, dentistry, osteotomy versus distraction, and rhinoplasty. The final CPGs were obtained after review by all stakeholders and allow cleft teams to base their treatment on current knowledge. With high-quality evidence lacking, the need for additional high-quality studies has become apparent.
Item Type: |
Journal Article (Review Article) |
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Division/Institute: |
04 Faculty of Medicine > School of Dental Medicine > Department of Orthodontics |
UniBE Contributor: |
Kuijpers-Jagtman, Anne-Marie |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
2077-0383 |
Publisher: |
MDPI |
Language: |
English |
Submitter: |
Renate Imhof-Etter |
Date Deposited: |
03 Jan 2022 15:31 |
Last Modified: |
05 Dec 2022 15:57 |
Publisher DOI: |
10.3390/jcm10214813 |
PubMed ID: |
34768332 |
Uncontrolled Keywords: |
cleft lip, alveolus and palate clinical practice guideline quality of health care recommendation clinical care treatment |
BORIS DOI: |
10.48350/162573 |
URI: |
https://boris.unibe.ch/id/eprint/162573 |
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