Evaluation of a porcine whole-limb heterotopic autotransplantation model

Kiermeir, David; Meoli, Martino; Müller, Sabine; Abderhalden, Susanne; Vögelin, Esther; Constantinescu, Mihai Adrian (2013). Evaluation of a porcine whole-limb heterotopic autotransplantation model. Microsurgery, 33(2), pp. 141-7. New York, N.Y.: Wiley-Liss 10.1002/micr.22038

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Recently performed vascularized composite tissue allotransplantations (CTAs) stimulate the ongoing research in the area of whole-limb transplantation. A reliable in vivo animal model is required for investigations in vascularized whole-limb CTA. The model should allow in vivo assessment in whole-limb preservation, allograft and xenograft response, and host immunomodulation. The goal of this study is to describe and evaluate the in vivo feasibility and reproducibility of a whole-limb porcine model as a basis for future research in this field.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Orthopaedic, Plastic and Hand Surgery (DOPH) > Clinic of Plastic and Hand Surgery > Plastic, Reconstructive and Aesthetic Surgery
04 Faculty of Medicine > Department of Orthopaedic, Plastic and Hand Surgery (DOPH) > Clinic of Plastic and Hand Surgery > Hand Surgery
04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Institute of Diagnostic, Interventional and Paediatric Radiology
04 Faculty of Medicine > Department of Orthopaedic, Plastic and Hand Surgery (DOPH) > Clinic of Plastic and Hand Surgery
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > Forschungsbereich Mu50 > Forschungsgruppe Herz und Gefässe

UniBE Contributor:

Kiermeir, David; Meoli, Martino; Müller, Sabine; Abderhalden, Susanne; Vögelin, Esther and Constantinescu, Mihai Adrian

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0738-1085

Publisher:

Wiley-Liss

Language:

English

Submitter:

Jörg Arnoldi

Date Deposited:

04 Oct 2013 14:40

Last Modified:

25 Mar 2014 14:38

Publisher DOI:

10.1002/micr.22038

PubMed ID:

22976431

Web of Science ID:

000314898400009

URI:

https://boris.unibe.ch/id/eprint/16297 (FactScience: 223905)

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