Winterhalter, C; Togno, M; Nesteruk, K P; Emert, F; Psoroulas, S; Vidal, M; Meer, D; Weber, D C; Lomax, A; Safai, S (2021). Faraday cup for commissioning and quality assurance for proton pencil beam scanning beams at conventional and ultra-high dose rates. Physics in medicine and biology, 66(12) Institute of Physics Publishing IOP 10.1088/1361-6560/abfbf2
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Recently, proton therapy treatments delivered with ultra-high dose rates have been of high scientific interest, and the Faraday cup (FC) is a promising dosimetry tool for such experiments. Different institutes use different FC designs, and either a high voltage guard ring, or the combination of an electric and a magnetic field is employed to minimize the effect of secondary electrons. The authors first investigate these different approaches for beam energies of 70, 150, 230 and 250 MeV, magnetic fields between 0 and 24 mT and voltages between -1000 and 1000 V. When applying a magnetic field, the measured signal is independent of the guard ring voltage, indicating that this setting minimizes the effect of secondary electrons on the reading of the FC. Without magnetic field, applying the negative voltage however decreases the signal by an energy dependent factor up to 1.3% for the lowest energy tested and 0.4% for the highest energy, showing an energy dependent response. Next, the study demonstrates the application of the FC up to ultra-high dose rates. FC measurements with cyclotron currents up to 800 nA (dose rates of up to approximately 1000 Gy s-1) show that the FC is indeed dose rate independent. Then, the FC is applied to commission the primary gantry monitor for high dose rates. Finally, short-term reproducibility of the monitor calibration is quantified within single days, showing a standard deviation of 0.1% (one sigma). In conclusion, the FC is a promising, dose rate independent tool for dosimetry up to ultra-high dose rates. Caution is however necessary when using a FC without magnetic field, as a guard ring with high voltage alone can introduce an energy dependent signal offset.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Radiation Oncology |
UniBE Contributor: |
Weber, Damien Charles |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
0031-9155 |
Publisher: |
Institute of Physics Publishing IOP |
Language: |
English |
Submitter: |
Beatrice Scheidegger |
Date Deposited: |
19 Jan 2022 14:39 |
Last Modified: |
05 Dec 2022 15:59 |
Publisher DOI: |
10.1088/1361-6560/abfbf2 |
PubMed ID: |
33906166 |
Uncontrolled Keywords: |
Faraday cup dosimetry proton therapy ultra-high dose rate |
BORIS DOI: |
10.48350/162979 |
URI: |
https://boris.unibe.ch/id/eprint/162979 |