Avascular Necrosis Bone Complication after Active COVID-19 Infection: Preliminary Results.

Sulewski, Adam; Sieroń, Dominik; Szyluk, Karol; Dąbrowski, Mikołaj; Kubaszewski, Łukasz; Lukoszek, Dawid; Christe, Andreas (2021). Avascular Necrosis Bone Complication after Active COVID-19 Infection: Preliminary Results. Medicina, 57(12) MDPI 10.3390/medicina57121311

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Background and objectives: The course of SARS-CoV-2 (COVID-19) is still under analysis. The majority of complications arising from the infection are related to the respiratory system. The adverse effect of the viral infection on bone and joint tissue has also been observed. Materials and Methods: We present a group of 10 patients with degeneration of large joints and adjacent epiphyses of long bones and the spine, with a background of bone infarctions and avascular necrosis (AVN) immediately after infection with the COVID-19 virus. In MR imaging, changes in the characteristics of AVN were documented. Results: Observation of this group showed a clear correlation among the history of COVID-19 disease in the patients, moderately severe symptoms, high levels of IgG antibodies, and the time of occurrence of joint changes. No other clinically significant complications were observed following COVID-19 infection in the study group. No other risk factors for AVN or autoimmune or degenerative diseases were found in the study group. The group of patients responded well to empirical treatment with steroids, which normalized acute inflammatory symptoms and pain in the joints. Conclusions: During coronavirus (COVID-19) infection, there are complications in the locomotor system, such as microembolism and the formation of AVN; hence, more research is needed.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Institute of Diagnostic, Interventional and Paediatric Radiology

UniBE Contributor:

Christe, Andreas

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1648-9144

Publisher:

MDPI

Language:

English

Submitter:

Maria de Fatima Henriques Bernardo

Date Deposited:

20 Jan 2022 08:18

Last Modified:

04 Aug 2023 17:54

Publisher DOI:

10.3390/medicina57121311

PubMed ID:

34946256

Uncontrolled Keywords:

SARS-CoV-2 infections avascular necrosis bone corticosteroids osteonecrosis

BORIS DOI:

10.48350/163166

URI:

https://boris.unibe.ch/id/eprint/163166

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