Sulewski, Adam; Sieroń, Dominik; Szyluk, Karol; Dąbrowski, Mikołaj; Kubaszewski, Łukasz; Lukoszek, Dawid; Christe, Andreas (2021). Avascular Necrosis Bone Complication after Active COVID-19 Infection: Preliminary Results. Medicina, 57(12) MDPI 10.3390/medicina57121311
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Background and objectives: The course of SARS-CoV-2 (COVID-19) is still under analysis. The majority of complications arising from the infection are related to the respiratory system. The adverse effect of the viral infection on bone and joint tissue has also been observed. Materials and Methods: We present a group of 10 patients with degeneration of large joints and adjacent epiphyses of long bones and the spine, with a background of bone infarctions and avascular necrosis (AVN) immediately after infection with the COVID-19 virus. In MR imaging, changes in the characteristics of AVN were documented. Results: Observation of this group showed a clear correlation among the history of COVID-19 disease in the patients, moderately severe symptoms, high levels of IgG antibodies, and the time of occurrence of joint changes. No other clinically significant complications were observed following COVID-19 infection in the study group. No other risk factors for AVN or autoimmune or degenerative diseases were found in the study group. The group of patients responded well to empirical treatment with steroids, which normalized acute inflammatory symptoms and pain in the joints. Conclusions: During coronavirus (COVID-19) infection, there are complications in the locomotor system, such as microembolism and the formation of AVN; hence, more research is needed.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Institute of Diagnostic, Interventional and Paediatric Radiology |
UniBE Contributor: |
Christe, Andreas |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1648-9144 |
Publisher: |
MDPI |
Language: |
English |
Submitter: |
Maria de Fatima Henriques Bernardo |
Date Deposited: |
20 Jan 2022 08:18 |
Last Modified: |
04 Aug 2023 17:54 |
Publisher DOI: |
10.3390/medicina57121311 |
PubMed ID: |
34946256 |
Uncontrolled Keywords: |
SARS-CoV-2 infections avascular necrosis bone corticosteroids osteonecrosis |
BORIS DOI: |
10.48350/163166 |
URI: |
https://boris.unibe.ch/id/eprint/163166 |
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