Bleeding avoidance strategies in percutaneous coronary intervention.

Capodanno, Davide; Bhatt, Deepak L; Gibson, C Michael; James, Stefan; Kimura, Takeshi; Mehran, Roxana; Rao, Sunil V; Steg, Philippe Gabriel; Urban, Philip; Valgimigli, Marco; Windecker, Stephan; Angiolillo, Dominick J (2022). Bleeding avoidance strategies in percutaneous coronary intervention. Nature reviews - cardiology, 19(2), pp. 117-132. Nature Publishing Group 10.1038/s41569-021-00598-1

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For many years, bleeding has been perceived as an unavoidable consequence of strategies aimed at reducing thrombotic complications in patients undergoing percutaneous coronary intervention (PCI). However, the paradigm has now shifted towards bleeding being recognized as a prognostically unfavourable event to the same extent as having a new or recurrent ischaemic or thrombotic complication. As such, in parallel with progress in device and drug development for PCI, there is clinical interest in developing strategies that maximize not only the efficacy but also the safety (for example, by minimizing bleeding) of any antithrombotic treatment or procedural aspect before, during or after PCI. In this Review, we discuss contemporary data and aspects of bleeding avoidance strategies in PCI, including risk stratification, timing of revascularization, pretreatment with antiplatelet agents, selection of vascular access, choice of coronary stents and antithrombotic treatment regimens.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiology

UniBE Contributor:

Windecker, Stephan

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1759-5010

Publisher:

Nature Publishing Group

Language:

English

Submitter:

Nadia Biscozzo

Date Deposited:

20 Jan 2022 09:43

Last Modified:

05 Dec 2022 15:59

Publisher DOI:

10.1038/s41569-021-00598-1

PubMed ID:

34426673

BORIS DOI:

10.48350/163192

URI:

https://boris.unibe.ch/id/eprint/163192

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