Bär, Sarah; Praz, Fabien; Räber, Lorenz (2021). Plaque erosion causing ST-elevation myocardial infarction after consumption of cannabis and N2O in a 27-year old man: a case report. BMC cardiovascular disorders, 21(1), p. 147. BioMed Central 10.1186/s12872-021-01953-3
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BACKGROUND
The recreational drugs cannabis and nitrous oxide (N2O) are known for pro-atherogenic effects and are associated with an elevated risk of myocardial infarction. These cardiovascular effects might be underestimated by the public. Culprit-lesion composition of myocardial infarctions associated with cannabis and N2O has been unknown so far. This case report aims to raise the awareness of the adverse cardiovascular effects of cannabis and N2O and reports, for the first time, optical coherence tomography (OCT) findings of the culprit lesion.
CASE PRESENTATION
This is a case report of a 27-year old man with anterior ST-segment-elevation myocardial infarction (STEMI) after intoxication with cannabis and N2O. Coronary angiography and OCT revealed plaque erosion with subsequent subtotal thrombotic occlusion of the left anterior descending artery that was successfully treated with 1 drug-eluting stent. The patient was symptom free at 6 months follow-up and had been able to abstain from drug consumption.
CONCLUSIONS
This is the first case to demonstrate the association between cannabis and N2O abuse and plaque erosion on OCT in a young man with STEMI. In contrast to smoking, whose adverse effects are well-known, the cardiovascular effects of cannabis and N2O might be underestimated. These adverse effects should gain more awareness in the public to prevent early vascular events in young adults.
Item Type: |
Journal Article (Further Contribution) |
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Division/Institute: |
04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiology |
UniBE Contributor: |
Bär, Sarah, Praz, Fabien Daniel, Räber, Lorenz |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1471-2261 |
Publisher: |
BioMed Central |
Language: |
English |
Submitter: |
Nadia Biscozzo |
Date Deposited: |
21 Jan 2022 07:40 |
Last Modified: |
05 Dec 2022 15:59 |
Publisher DOI: |
10.1186/s12872-021-01953-3 |
PubMed ID: |
33757456 |
Uncontrolled Keywords: |
Case report Drug abuse Optical coherence tomography Percutaneous coronary intervention Plaque erosion ST-elevation myocardial infarction |
BORIS DOI: |
10.48350/163254 |
URI: |
https://boris.unibe.ch/id/eprint/163254 |
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