Plaque erosion causing ST-elevation myocardial infarction after consumption of cannabis and N2O in a 27-year old man: a case report.

Bär, Sarah; Praz, Fabien; Räber, Lorenz (2021). Plaque erosion causing ST-elevation myocardial infarction after consumption of cannabis and N2O in a 27-year old man: a case report. BMC cardiovascular disorders, 21(1), p. 147. BioMed Central 10.1186/s12872-021-01953-3

[img]
Preview
Text
Plaque_erosion_causing_ST-elevation_myocardial.pdf - Published Version
Available under License Creative Commons: Attribution (CC-BY).

Download (1MB) | Preview

BACKGROUND

The recreational drugs cannabis and nitrous oxide (N2O) are known for pro-atherogenic effects and are associated with an elevated risk of myocardial infarction. These cardiovascular effects might be underestimated by the public. Culprit-lesion composition of myocardial infarctions associated with cannabis and N2O has been unknown so far. This case report aims to raise the awareness of the adverse cardiovascular effects of cannabis and N2O and reports, for the first time, optical coherence tomography (OCT) findings of the culprit lesion.

CASE PRESENTATION

This is a case report of a 27-year old man with anterior ST-segment-elevation myocardial infarction (STEMI) after intoxication with cannabis and N2O. Coronary angiography and OCT revealed plaque erosion with subsequent subtotal thrombotic occlusion of the left anterior descending artery that was successfully treated with 1 drug-eluting stent. The patient was symptom free at 6 months follow-up and had been able to abstain from drug consumption.

CONCLUSIONS

This is the first case to demonstrate the association between cannabis and N2O abuse and plaque erosion on OCT in a young man with STEMI. In contrast to smoking, whose adverse effects are well-known, the cardiovascular effects of cannabis and N2O might be underestimated. These adverse effects should gain more awareness in the public to prevent early vascular events in young adults.

Item Type:

Journal Article (Further Contribution)

Division/Institute:

04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiology

UniBE Contributor:

Bär, Sarah, Praz, Fabien Daniel, Räber, Lorenz

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1471-2261

Publisher:

BioMed Central

Language:

English

Submitter:

Nadia Biscozzo

Date Deposited:

21 Jan 2022 07:40

Last Modified:

05 Dec 2022 15:59

Publisher DOI:

10.1186/s12872-021-01953-3

PubMed ID:

33757456

Uncontrolled Keywords:

Case report Drug abuse Optical coherence tomography Percutaneous coronary intervention Plaque erosion ST-elevation myocardial infarction

BORIS DOI:

10.48350/163254

URI:

https://boris.unibe.ch/id/eprint/163254

Actions (login required)

Edit item Edit item
Provide Feedback