Knecht, Sven; Sticherling, Christian; Roten, Laurent; Badertscher, Patrick; Chollet, Laurève; Küffer, Thomas; Spies, Florian; Madaffari, Antonio; Mühl, Aline; Baldinger, Samuel H.; Servatius, Helge; Osswald, Stefan; Reichlin, Tobias; Kühne, Michael (2022). Technical and procedural comparison of two different cryoballoon ablation systems in patients with atrial fibrillation. Journal of interventional cardiac electrophysiology, 64(2), pp. 409-416. Springer 10.1007/s10840-021-01035-6
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PURPOSE
The aim was to report procedural and technical differences of a novel cryoballoon (NCB) ablation catheter for pulmonary vein isolation (PVI) compared to the standard cryoballoon (SCB) catheter.
METHODS
Consecutive patients with atrial fibrillation (AF) undergoing PVI using the NCB and the SCB were included. Procedural parameters, technical differences, acute efficacy, and safety are reported.
RESULTS
Eighty patients (age 66 ± 10 years, ejection fraction 57 ± 10%, left atrial volume index 40 ± 6 ml/m2) were studied. With the NCB, 156 of 158 PVs (99%) were isolated compared to isolation of 159 of 159 PVs (100%) with the SCB. The median number of freezes in the NCB and the SCB group was 6 (IQR 5-8) and 5 (IQR 4-7), respectively (p = 0.051), with 73% and 71% of the PVs isolated with a single freeze, respectively. Nadir temperature and temperature at isolation were - 59 ± 6 °C and - 45 ± 17 °C in the NCB group and - 46 ± 7 °C and - 32 ± 23 °C in the SCB group, respectively (both p < 0.001) with no difference in time to isolation (TTI). Procedural differences were observed for the total procedure time (84 ± 29 min in the NCB group and 65 ± 17 min in the SCB group, p = 0.003). There was a peri-procedural stroke in one patient in the NCB group. Differences in catheter design were observed that may account for the differences in temperature recordings and ice cap formation.
CONCLUSIONS
Acute efficacy and TTI were similar with the NCB compared to the SCB. Measured temperatures were lower with the NCB, most likely due to differences in catheter design.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiology |
UniBE Contributor: |
Roten, Laurent, Chollet, Laurève Mélisande, Kueffer, Thomas, Madaffari, Antonio, Mühl, Aline, Baldinger, Samuel Hannes, Servatius, Helge Simon (A), Reichlin, Tobias Roman |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1383-875X |
Publisher: |
Springer |
Language: |
English |
Submitter: |
Vjollca Coli |
Date Deposited: |
21 Jan 2022 11:59 |
Last Modified: |
29 Mar 2023 23:38 |
Publisher DOI: |
10.1007/s10840-021-01035-6 |
PubMed ID: |
34319493 |
Uncontrolled Keywords: |
Atrial fibrillation Cryoballoon ablation Technical specification |
BORIS DOI: |
10.48350/163325 |
URI: |
https://boris.unibe.ch/id/eprint/163325 |
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