Impact of progesterone on skin and hair in menopause - a comprehensive review.

Gasser, S; Heidemeyer, K; von Wolff, M; Stute, P (2021). Impact of progesterone on skin and hair in menopause - a comprehensive review. Climacteric, 24(3), pp. 229-235. Taylor & Francis 10.1080/13697137.2020.1838476

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In clinical practice, micronized progesterone (MP) is frequently recommended to treat signs and symptoms of skin and hair aging in menopausal women. The aim of this comprehensive review was to evaluate whether topically or systemically applied MP may effectively prevent or slow down signs of skin and hair aging. Three out of six identified studies reported an impact of MP on skin aging markers in menopausal women. Of these, two studies reported a benefit: one for topically applied MP, another for systemically applied combined menopausal hormone therapy (MHT) comprising MP as progestogen for endometrial protection. Tolerability and safety of MP were good. However, there was no study investigating the impact of MP on menopausal scalp hair. In conclusion, delay of skin aging comprises lifestyle adjustment, antioxidants, and several esthetic procedures. In menopausal women, MHT displays beneficial effects on skin aging. There is poor quality but promising scientific evidence for MP displaying anti-aging skin effects in menopausal women. However, good quality studies are needed.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Dermatology
04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Gynaecology

UniBE Contributor:

Heidemeyer, Kristine, von Wolff, Michael, Stute, Petra

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1473-0804

Publisher:

Taylor & Francis

Language:

English

Submitter:

Monika Zehr

Date Deposited:

02 Feb 2022 11:04

Last Modified:

05 Dec 2022 16:01

Publisher DOI:

10.1080/13697137.2020.1838476

PubMed ID:

33527841

Uncontrolled Keywords:

Progesterone anti-aging hair hormone therapy menopause skin sleep

URI:

https://boris.unibe.ch/id/eprint/163759

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