Aubry, Evelyne M; Raio, Luigi; Oelhafen, Stephan (2021). Effect of the IADPSG screening strategy for gestational diabetes on perinatal outcomes in Switzerland. Diabetes research and clinical practice, 175, p. 108830. Elsevier 10.1016/j.diabres.2021.108830
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AIMS
To evaluate the impact adoption of the International Association of Diabetes and Pregnancy Study Groups (IADPSG) criteria on prevalence of gestational diabetes mellitus (GDM) and risks of perinatal outcomes.
METHODS
Retrospectively, 155,103 women screened with selective two step criteria in Switzerland in period 1 (2005-2010) were compared to 170,427 women screened with IADPSG criteria in period 2 (2012-2017). GDM prevalence over time was established and multivariable regression used to assess variation in risks for GDM related events and perinatal outcomes.
RESULTS
GDM prevalence increased steadily over both study periods from 1.8% to 9.0%. A risk reduction of GDM-related events was shown only for women with one or two risk factors for GDM present (relative risk (95% confidence interval)): (0.93 (0.90,0.97), 0.90 (0.83,0.96)). The comparison of perinatal outcomes between the two study periods revealed a significant lower risk for newborns large for gestational age (LGA) (0.93 (0.91-0.95)), pre-term delivery (0.94 (0.92-0.97)) and neonatal hypoglycemia (0.83 (0.77-0.90)) in period 2.
CONCLUSION
The introduction of the IADPSG criteria for the screening of GDM increased prevalence by threefold with no substantial improvements in GDM related events for women without risk factors but reduced the risks for LGA, neonatal hypoglycemia and preterm birth.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Gynaecology |
UniBE Contributor: |
Raio, Luigi |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
0168-8227 |
Publisher: |
Elsevier |
Language: |
English |
Submitter: |
Monika Zehr |
Date Deposited: |
02 Feb 2022 10:25 |
Last Modified: |
05 Dec 2022 16:01 |
Publisher DOI: |
10.1016/j.diabres.2021.108830 |
PubMed ID: |
33895193 |
Uncontrolled Keywords: |
Gestational diabetes mellitus International Association of the Diabetes and Pregnancy Study Groups Perinatal outcomes Prevalence |
BORIS DOI: |
10.48350/163857 |
URI: |
https://boris.unibe.ch/id/eprint/163857 |
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